Releases
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Study reveals missing link between high-fat diet, microbiota and heart disease
A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science. Read MoreAug 12, 2021
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Verrier creates remote program for Latin American band directors
Vanderbilt Blair creates Curso Virtual de Dirección de Banda, a remote learning program for music directors in Latin America that covers instrument pedagogy, conducting techniques and other topics in band direction. Read MoreAug 10, 2021
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Vitamin D impact on disease biomarkers
In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease. Read MoreAug 10, 2021
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Motor protein linked to intestinal cell differentiation
The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read MoreAug 5, 2021
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Gene expression in diabetic nephropathy
Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read MoreAug 5, 2021
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Research Snapshot: Vanderbilt engineer the first to introduce low-power dynamic manipulation of single nanoscale quantum objects
Assistant Professor of electrical engineering Justus Ndukaife is powering the quantum computing revolution with the development of the first on-demand, scalable technique to manipulate nanoscale nanodiamonds. Est. reading time: 2 mins. Read MoreJul 30, 2021
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Prediction models for breast cancer
Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read MoreJul 27, 2021
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Mood and cognition after chemotherapy
Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read MoreJul 26, 2021
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For more precise drug treatments, ‘squeeze’ the genome: study finds
Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center. Read MoreJul 22, 2021
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Influenza network sizes up COVID
Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients. Read MoreJul 22, 2021
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Establishing HIV care in Tennessee
Vanderbilt researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population. Read MoreJul 13, 2021
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Probing statin-associated diseases with genetics
Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases. Read MoreJul 12, 2021
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Nature’s “recycler” could reduce heart disease risk: study
Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material. Read MoreJul 8, 2021
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Study finds genetic risk factors for severe COVID-19 illness
A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness. Read MoreJul 8, 2021
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Delirium and mortality reexamined
A multicenter study of ICU patients found that in the hospital, delirium was associated with a nearly three-fold increase in risk of death the following day, but after discharge there was no association between delirium and mortality. Read MoreJul 8, 2021
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Genetics of hydrocephalus
Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition. Read MoreJul 8, 2021
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Treating metastatic prostate cancer
An indirect comparative effectiveness study using published data suggests that the targeted therapy olaparib should be re-evaluated for treating metastatic prostate cancer. Read MoreJun 22, 2021
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Combination antibody therapies should retain effectiveness against emerging COVID-19 variants: study
Five monoclonal antibody “cocktails,” including one developed at Vanderbilt University Medical Center (VUMC), are protective in animal studies against several variant strains of COVID-19, according to a report this week in the journal Nature. Read MoreJun 22, 2021
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Dexmedetomidine and delirium
The sedative dexmedetomidine, when administered during or after heart surgery, is associated with postoperative delirium and adverse outcomes. Read MoreJun 21, 2021
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COVID-19 complication underdiagnosed
A mysterious inflammatory syndrome linked to COVID-19 infection and first identified in children also occurs in adults, Vanderbilt researchers report. Read MoreJun 17, 2021