School Of Medicine Basic Sciences
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New therapeutic target for lung cancer
Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer. Read MoreNov 12, 2020
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Ask an Expert: What effect has the pandemic had on the opioid crisis?
Erin Calipari, assistant professor of pharmacology and of psychiatry and behavioral sciences, discusses the COVID-19 pandemic's impact on those struggling with opioid addiction. Read MoreNov 10, 2020
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Vanderbilt biologist uses rabies-like virus to illuminate how SARS-CoV-2 blocks immune response
Yi Ren, assistant professor of biochemistry, has contributed to research on the function and impact of the SARS-CoV-2 protein on immune signaling protein in host cells. This understanding may lead to the development of immune-enhancing therapeutics. Read MoreNov 9, 2020
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Discovery Science Emerging Scholars Lecture: ‘Investigating the molecular regulation and function of death signaling complexes’ Nov. 19
Cornelius Taabazuing, a postdoctoral fellow at the Memorial Sloan-Kettering Cancer Center, will present “Investigating the molecular regulation and function of death signaling complexes.” The Discovery Science Emerging Scholars Lecture is scheduled for Thursday, Nov. 19, at 9:30 a.m. via Zoom. Read MoreNov 8, 2020
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Ren’s lab advances SARS-CoV-2 research and prioritizes safety during Research Ramp-up
Assistant Professor of Biochemistry Yi Ren and her team have made several discoveries to illuminate the mechanisms of key host-pathogen interactions involving viruses, with implications for gaining a better understanding of SARS-CoV-2, the virus that causes COVID-19. Read MoreNov 6, 2020
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Nancy Carrasco’s pioneering public health work recognized with National Academy of Medicine election
Nancy Carrasco, professor and chair of the Department of Molecular Physiology and Biophysics and the Joe C. Davis Chair of Biomedical Science, receives one of the highest honors in health and medicine. Read MoreNov 4, 2020
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Spontaneous release of neurotransmitters in the brain identified as a culprit of developmental disorders in infants and children
Vanderbilt researchers discover how a group of neurodevelopmental disorders ranging in severity are caused in infants and children, opening new avenues for therapeutics. Read MoreNov 3, 2020
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Jerri Rook is awarded the Alzheimer’s Drug Discovery Foundation’s prestigious Melvin R. Goodes prize
Behavioral and systems neuropharmacologist Jerri Rook is recognized by the Alzheimer’s Drug Discovery Foundation with the Goodes Prize to continue her work in Alzheimer’s disease research. Read MoreNov 2, 2020
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Histamine circuits in brain reward center
Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction. Read MoreOct 29, 2020
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Vanderbilt University anti-inflammatory therapy licensed to Amytrx is now in clinical trials for eczema treatment
Jacek Hawiger’s anti-inflammatory peptide therapy, licensed by Amytrx and now in clinical trials, has the potential to safely and effectively treat a multitude of inflammatory and metabolic diseases. Read MoreOct 27, 2020
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Vanderbilt biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people. Read MoreOct 27, 2020
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New faculty Richard Sando: A better understanding of brain circuitry
New Assistant Professor of Pharmacology Rick Sando is interested in how neural circuits carry out specific functions when activated—and why these processes sometimes go awry. Read MoreOct 26, 2020
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Interdisciplinary melanoma research brings understanding of cellular resistance to cancer treatment, opening doors to new cures
Drug-tolerant persister cells–those that survive cancer treatment–found to rely on similar survival mechanisms across cancers, in a groundbreaking study led by Vanderbilt researchers. Read MoreOct 21, 2020
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Warren Center for Neuroscience Drug Discovery names Craig Lindsley as director
Craig Lindsley, the William K. Warren, Jr. Chair and University Professor of Pharmacology, Biochemistry and Chemistry, will become director of Vanderbilt University’s Warren Center for Neuroscience Drug Discovery, effective Dec. 1, 2020. Read MoreOct 20, 2020
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Three from Vanderbilt elected to the National Academy of Medicine
Three Vanderbilt University faculty members have been elected this year to the National Academy of Medicine, the organization announced Oct. 19. Read MoreOct 20, 2020
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Three from Vanderbilt elected to the National Academy of Medicine
Three Vanderbilt faculty members—Nancy Carrasco, Velma McBride Murry and Consuelo Wilkins—have been elected this year to the National Academy of Medicine, the organization announced on Monday. Read MoreOct 20, 2020
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Preserving gut mucus architecture
A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens. Read MoreOct 20, 2020
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Discovery Sciences Emerging Scholars Lecture features Princeton’s McReynolds Oct. 29
Melanie McReynolds, HHMI Hanna H. Gray Fellow at Princeton University, will present “NAD+ Flux is Maintained in Aged Mice” on Thursday, Oct. 29, at 9:30 a.m. via Zoom. This Discovery Sciences Emerging Scholars Lecture is co-sponsored by the Department of Molecular Physiology and Biophysics. Read MoreOct 19, 2020
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Vanderbilt researchers make counterintuitive discoveries about immune-like characteristics of cells, chemotherapy’s impact on tissue growth
Biologists reveal that tissue perturbations by chemotherapy agents promote stem cell expansion and that fibroblast cells exhibit unexpected, immune-like behavior. Read MoreOct 15, 2020
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Possible COVID-19 “decoy”
It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read MoreOct 15, 2020