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NIDDK Archives

Boosting beta cells in diabetes

Apr. 20, 2015—New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas.

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Surprising finding in the kidney

Apr. 16, 2015—TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling.

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New player in heart cell growth

Apr. 6, 2015—Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy.

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Tiny model of diabetes

Feb. 20, 2015—Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment.

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Kidney disease impacts HDL function

Feb. 11, 2015—Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.

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New clue to a devastating disease

Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

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Beta cell link to fasting glucose

Jan. 22, 2015—New findings explain why variation in a particular gene is the most important determinant of fasting blood glucose levels in humans.

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Target for atherosclerosis therapies

Dec. 17, 2014—A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

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New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

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Protein implicated in atherosclerosis

Nov. 25, 2014—Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.

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New insight on oral cancer culprits

Nov. 12, 2014—A new mouse model offers insight into the signaling pathways that control oral cancers – and a platform for testing anticancer therapeutics.

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Neuronal culprit in genetic disease

Oct. 14, 2014—A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.

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