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NIDDK Archives

Target for atherosclerosis therapies

Dec. 17, 2014—A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression.

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New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

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Protein implicated in atherosclerosis

Nov. 25, 2014—Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.

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New insight on oral cancer culprits

Nov. 12, 2014—A new mouse model offers insight into the signaling pathways that control oral cancers – and a platform for testing anticancer therapeutics.

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Neuronal culprit in genetic disease

Oct. 14, 2014—A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.

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Patient-derived stem cells shed light on pulmonary hypertension

Sep. 16, 2014—Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.

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Protein interaction protects against neurodegeneration

Sep. 2, 2014—Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration.

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Weight regain after gastric bypass

Aug. 15, 2014—Early weight regain after gastric bypass surgery does not reverse metabolic improvements, and the "hunger hormone" ghrelin might indicate who is susceptible to weight regain.

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Photo: Summer research conference

Jul. 31, 2014—Undergraduates from across the country attended a summer research conference at Vanderbilt this week sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases.

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Magnuson honored for role in Beta Cell Biology Consortium

Jul. 24, 2014—Mark Magnuson, M.D., Louise B. McGavock Professor of Molecular Physiology and Biophysics at Vanderbilt University, has received a national leadership award for the Beta Cell Biology Consortium (BCBC), a major team science initiative.

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Molecular ‘chat’ holds kidney fibrosis clues

Jul. 10, 2014—A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

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CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

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