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NIDDK Archives

Protein interaction protects against neurodegeneration

Sep. 2, 2014—Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration.

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Weight regain after gastric bypass

Aug. 15, 2014—Early weight regain after gastric bypass surgery does not reverse metabolic improvements, and the "hunger hormone" ghrelin might indicate who is susceptible to weight regain.

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Photo: Summer research conference

Jul. 31, 2014—Undergraduates from across the country attended a summer research conference at Vanderbilt this week sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases.

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Magnuson honored for role in Beta Cell Biology Consortium

Jul. 24, 2014—Mark Magnuson, M.D., Louise B. McGavock Professor of Molecular Physiology and Biophysics at Vanderbilt University, has received a national leadership award for the Beta Cell Biology Consortium (BCBC), a major team science initiative.

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Molecular ‘chat’ holds kidney fibrosis clues

Jul. 10, 2014—A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

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CaMKII enhances insulin secretion

May. 14, 2014—The protein CaMKII acts as a calcium sensor in a positive feedback pathway that enhances glucose-stimulated insulin secretion.

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PET probe detects dying tumor cells

May. 8, 2014—A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

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Increased cell permeability may protect from colitis

Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

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Nutrient-absorbing surface’s assembly revealed: study

Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.

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Channel drug restores glucose balance

Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

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Matrix remodeling and insulin resistance

Apr. 10, 2014—The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

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Development and disease in the aorta

Apr. 2, 2014—Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease.

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