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NIDDK

A new regulator of B cell development

Oct. 8, 2019—New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

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A step toward gastric cancer

Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.

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Treating C. diff: new purpose for an old drug?

Sep. 24, 2019—An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

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Microvilli in motion

Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

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Host-microbe interactions in the gut

Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

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Pancreatic cancer clue

Aug. 12, 2019—Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.

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A probiotic treatment for obesity?

Aug. 8, 2019—Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

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Intestinal immune cell interactions

Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

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New role for microtubules in diabetes

Jul. 29, 2019—Microtubules, part of the cell's cytoskeleton, regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.

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Sex differences in kidney injury

Jul. 25, 2019—Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

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New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

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Microbiome links diet to health

Jun. 20, 2019—Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health.

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