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NIDDK

Host-microbe interactions in the gut

Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

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Pancreatic cancer clue

Aug. 12, 2019—Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.

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A probiotic treatment for obesity?

Aug. 8, 2019—Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

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Intestinal immune cell interactions

Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

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New role for microtubules in diabetes

Jul. 29, 2019—Microtubules, part of the cell's cytoskeleton, regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.

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Sex differences in kidney injury

Jul. 25, 2019—Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.

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New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

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Microbiome links diet to health

Jun. 20, 2019—Vanderbilt researchers have discovered that the gut microbiome composition modulates how dietary nutrients are metabolized, with potential downstream consequences on metabolic health.

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Reprogramming cells for kidney repair

Mar. 14, 2019—Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments.

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Adhesion protein optimizes border

Feb. 15, 2019—Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning.

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New target for chronic kidney disease

Jan. 31, 2019—Craig Brooks and colleagues have identified a mechanism of kidney fibrosis progression, suggesting a potential new angle for treating chronic kidney disease.

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Building a pancreas

Jan. 17, 2019—Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop.

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