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NIDDK

Reprogramming cells for kidney repair

Mar. 14, 2019—Lauren Woodard and Matthew Wilson have discovered a way to reprogram adult human kidney cells into cells similar to those that form during embryonic development, which could lead to new kidney disease treatments.

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Adhesion protein optimizes border

Feb. 15, 2019—Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning.

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New target for chronic kidney disease

Jan. 31, 2019—Craig Brooks and colleagues have identified a mechanism of kidney fibrosis progression, suggesting a potential new angle for treating chronic kidney disease.

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Building a pancreas

Jan. 17, 2019—Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop.

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Pain relievers a risk for C. diff?

Jan. 17, 2019—David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers.

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Beta cell biomarker findings may speed diabetes research

Nov. 30, 2018—Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes.

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Green tea and diabetes

Nov. 30, 2018—A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism.

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Analyzing single-cell landscapes

Nov. 30, 2018—Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies.

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Team’s findings show glutamine metabolism affects T cell signaling

Nov. 1, 2018—Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases.

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Targeting diabetic kidney disease

Oct. 16, 2018—Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease.

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Insulin accelerant

Oct. 16, 2018—Reducing nitric oxide helps insulin move more quickly through blood vessels, find David Wasserman and colleagues.

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Mass spectrometry team earns grant to map body at the cellular level

Sep. 28, 2018—Biochemistry professor Richard Caprioli, director of the Mass Spectrometry Research Center, and Jeff Spraggins, research assistant professor of biochemistry, and their team will build a platform to molecularly characterize cells.

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