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NIDDK Archives

Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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Major grant to enhance kidney disease research

Sep. 28, 2017—Vanderbilt’s Division of Nephrology and Hypertension has received a five-year, $5 million federal grant to provide core research services in the fight against kidney disease.

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Acid reflux cancer link

Sep. 14, 2017—Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

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Early drivers of gastric cancer

Aug. 8, 2017—Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.

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HDAC3 role in B-cell development

Aug. 3, 2017—The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

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Student’s summer research program honors her mother

Jul. 27, 2017—As a teenager, Ashley Duhon realized she wanted to become a doctor so she could help people, like her mother, who suffer from medical complications due to type 1 diabetes.

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VUMC team’s discovery could lead to new diabetes treatment

Jun. 15, 2017—High circulating glucose, the hallmark of diabetes, is linked to the disease’s most serious complications including heart disease, kidney failure, blindness and amputation. Diabetes is the sixth leading cause of death and costs the nation an estimated $322 billion a year. Restoring the action of insulin has been the traditional treatment route. Insulin, a hormone...

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PET imaging to predict tumor response

Jun. 14, 2017—A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

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Flip side of gut protection

Jun. 9, 2017—Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease.

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NIDDK renews Vanderbilt’s diabetes research grant

Jun. 8, 2017—The Vanderbilt Diabetes Research and Training Center (VDRTC) is celebrating its 44th year of operation with a five-year competitive renewal of its $9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH).

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EETs contribute to insulin sensitivity

May. 11, 2017—Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

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