NIDDK

Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read More

A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read More

Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory. Read More

Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop. Read More

The use of human pancreatic islets to conduct diabetes-related research has greatly expanded in recent years, and a Human Islet Phenotyping Program (HIPP) at Vanderbilt University Medical Center has been established to provide important islet data to investigators worldwide. Read More

Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies. Read More

A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas. Read More

New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read More

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health. Read More

Vanderbilt’s Division of Nephrology and Hypertension has received a five-year, $5 million federal grant to provide core research services in the fight against kidney disease. Read More

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read More

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read More

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies. Read More

As a teenager, Ashley Duhon realized she wanted to become a doctor so she could help people, like her mother, who suffer from medical complications due to type 1 diabetes. Read More

High circulating glucose, the hallmark of diabetes, is linked to the disease’s most serious complications including heart disease, kidney failure, blindness and amputation. Diabetes is the sixth leading cause of death and costs the nation an estimated $322 billion a year. Restoring the action of insulin has been the traditional… Read More

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models. Read More

Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease. Read More

The Vanderbilt Diabetes Research and Training Center (VDRTC) is celebrating its 44th year of operation with a five-year competitive renewal of its $9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH). Read More

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read More

A new protein structure may guide the development of Alzheimer's therapeutics. Read More