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Department of Biochemistry

A catalog of DNA replication proteins

Oct. 3, 2019—Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.

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New faculty Houra Merrikh: On a collision course with antibiotic resistance

Sep. 29, 2019—Professor of Biochemistry Houra Merrikh distinctly remembers the day the email showed up in her inbox. Sent from the Bill and Melinda Gates Foundation, it was an invitation to present her research to someone named “Bill”—no last name included—in two days’ time.

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Guengerich, Sanders-Bush named ASPET fellows

Sep. 20, 2019—Vanderbilt University’s F. Peter (Fred) Guengerich, PhD, and Elaine Sanders-Bush, PhD, are among 22 prominent scientists named this week to the inaugural class of fellows of the American Society for Pharmacology and Experimental Therapeutics (ASPET).

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How nerves may lose their insulation

Aug. 22, 2019—Vanderbilt’s Bruce Carter and colleagues have discovered how genetic changes in the protein PMP22 may contribute to a disease of peripheral nerves.

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Team’s study reveals details of new DNA repair pathway

Jul. 25, 2019—Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

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A critical factor for wound healing

Jul. 16, 2019—Vanderbilt-Ingram Cancer Center scientists have discovered a role for a tumor suppressor protein in skin wound healing.

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Potential probe for early ovarian cancer

Jun. 20, 2019—Larry Marnett and colleagues have developed what may become the first agent for targeted PET imaging of cancer tissues, such as ovarian cancer, that express high levels of the COX-1 enzyme.

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Steroid binding to metabolic enzyme

Jun. 12, 2019—Understanding how a steroid-metabolizing enzyme binds to its substrates may aid in designing drugs to treat sexual dysfunction as well as prostate cancer.

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Novel DNA repair mechanism preserves genome integrity: study

Feb. 28, 2019—David Cortez and colleagues have discovered a new DNA repair mechanism.

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Lindsley named fellow of National Academy of Inventors

Jan. 4, 2019—Craig Lindsley, co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been named a fellow of the National Academy of Inventors.

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Merrikh Lab working to defeat drug-resistant superbugs

Dec. 20, 2018—New Vanderbilt University biochemistry professor Houra Merrikh is working to defeat drug-resistant superbugs by blocking a molecule they need to mutate rapidly.

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Rothamel selected as Vanderbilt Prize Student Scholar

Oct. 25, 2018—Katherine Rothamel, a Ph.D. student in the Department of Biochemistry at Vanderbilt University School of Medicine, has been selected as the 2017 Vanderbilt Prize Student Scholar.

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