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Department of Biochemistry Archives

Frontiers in Biochemistry seminar series kicks off Aug. 18

Jun. 28, 2017—University of Chicago professor Chuan He will discuss “RNA Methylation in Gene Expression Regulation” from noon to 1 p.m. Aug. 18 in Light Hall, Room 2014, to kick off the Frontiers in Biochemistry seminar series for 2017-18. Talks in the series take place at noon on select Fridays during the school year, with prestigious speakers invited from around the United States.

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Repriming replication roadblocks

Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

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Oxidative stress in tumors

May. 18, 2017—Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

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Protein structure may aid in treating Alzheimer’s disease

Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.

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A new mode of DNA repair

Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

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Fighting fungal infections

Apr. 3, 2017—A detailed structural and functional analysis of the yeast protein that is the main target of antifungal drugs will help direct efforts to develop better treatments.

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Team identifies ‘switch’ involved in DNA replication  

Feb. 23, 2017—DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.”

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COX-2 ‘conjugate’ may slow growth of some tumors: study

Jan. 19, 2017—More than a decade after the anti-inflammatory drugs Vioxx and Bextra were pulled from the market because of a heightened risk of heart attack and stroke in some patients, COX-2 inhibitors may be on the verge of a comeback, this time as anti-cancer agents.

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Graduate student’s cancer studies land NCI support

Nov. 17, 2016—Kamakoti “Kami” Bhat, a fifth-year graduate student in the lab of David Cortez, Ph.D., professor of Biochemistry in the School of Medicine, has achieved a “first” for Vanderbilt University.

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DNA damage response protein

Oct. 21, 2016—Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.

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Imaging probe for retinal disease

Oct. 12, 2016—An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.

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Basic science, extraordinary impact

Oct. 6, 2016—The discoveries that can change the course of human health forever often begin in the tiniest places: in molecules and cells, at the most fundamental intersection of physics, chemistry and biology. Understanding how these cellular and molecular processes work is the focus of basic biomedical research at Vanderbilt.

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