Research

A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. Read More

Vanderbilt University Medical Center is playing a key role in the HERO program, a national effort to establish a registry of U.S. health care workers and test whether the anti-malarial drug hydroxychloroquine will protect them, their patients and their families from COVID-19. Read More

Vanderbilt University Medical Center is leading a clinical trial to understand if a well-known drug used for malaria and rheumatologic conditions is safe and effective in treating hospitalized adults with COVID-19. Read More

Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease. Read More

Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders. Read More

Spasticity — a consequence of stroke and other disorders of the central nervous system — may be underdiagnosed and undertreated in nursing home residents. Read More

Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease. Read More

New insights on influenza genome packaging could guide strategies for interfering with the virus's life cycle and ability to cause infection. Read More

Runners could soon keep up with cyclists, thanks to a new exoskeleton invention from a team of mechanical engineers at Vanderbilt which would bring cycling mechanics to the human body. Read More

Researchers at Vanderbilt University Medical Center are playing a key role in the development of a potential new antiviral drug to treat COVID-19. Read More

Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. Read More

Hiba Baroud has received a 2020 NSF Faculty Early CAREER Development grant to boost community resilience and sustainability through a three-pronged project that starts with a better understanding of how people and infrastructures interact during hazards. Read More

This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain. Read More

A new cellular biology study reports the first visualization of a unique shape-shifting structure in the human body which plays an important role in the timely delivery of fats and proteins.  Read More

Red and processed meat intakes are strongly associated with increased risk of sessile serrated polyps, which are not as well studied as conventional adenomas. Read More

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth. Read More

A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients. Read More

According to a new study published by biological science researchers at Vanderbilt, the answer to eating (or fasting) windows lies in the circadian rhythms of the body’s biological clock.  Read More

A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk. Read More

Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat. Read More