NIGMS

  • red and blue boxing gloves

    Novel infection fighter

    A drug in use clinically to help make vaccines more effective may be a powerful new tool for fighting antibiotic-resistant infections. Read More

    Jun. 13, 2018

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    Confronting TB resistance

    Vanderbilt researchers describe how certain tuberculosis treatments work and suggest these medications may overcome the threat of drug-resistant tuberculosis. Read More

    Jun. 11, 2018

  • HIV virus

    A “public” target for HIV

    Common sequences of antibodies against HIV may be key to developing a successful vaccine strategy for the virus. Read More

    Jun. 8, 2018

  • 3d rendering white blood cells with red blood cells

    Putting the brakes on sepsis

    An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read More

    May. 9, 2018

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    Toxin floats on lipid rafts

    The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More

    Apr. 23, 2018

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    How the skin protects

    Treatments for common skin conditions such as atopic dermatitis may be improved by understanding the enzymes responsible for forming the skin’s water-tight barrier. Read More

    Apr. 19, 2018

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    New view of the heartbeat

    Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read More

    Apr. 6, 2018

  • abstract mage of lungs

    Lung diseases share molecular signature

    Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read More

    Apr. 5, 2018

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    What protein is that?

    An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research. Read More

    Mar. 28, 2018

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    New imaging approach offers unprecedented views of staph infection

    A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state. Read More

    Mar. 15, 2018

  • ekg results

    Long QT syndrome – revealed

    Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read More

    Mar. 12, 2018

  • busy intersection

    Iron-sulfur “intersection”

    Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia. Read More

    Mar. 8, 2018

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    Structure of a stem cell niche

    Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read More

    Feb. 28, 2018

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    Muscular dystrophy clue

    Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy. Read More

    Feb. 9, 2018

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    Cell skeleton and the brush border

    Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read More

    Jan. 31, 2018

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    Imaging features predict tumor grade

    Vanderbilt researchers have discovered imaging features associated with increased risk for aggressive meningiomas (tumors of the brain membranes) that could help guide surgical planning and patient counseling. Read More

    Jan. 29, 2018

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    Number of minority trainees on rise, but not minority faculty

    Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty. Read More

    Jan. 25, 2018

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    HDL and kidney injury after surgery

    Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered. Read More

    Jan. 17, 2018

  • conceptual - glowing cell

    Lighting up iron levels

    A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read More

    Jan. 11, 2018

  • little girl using inhaler

    Asthma study may point to potential new therapeutic approach

    New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read More

    Jan. 4, 2018