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NIGMS Archives

Long QT syndrome – revealed

Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.

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Iron-sulfur “intersection”

Mar. 8, 2018—Vanderbilt researchers have discovered an unanticipated link between sulfur and iron balance, pointing to a genetic basis for iron-deficiency anemia.

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Structure of a stem cell niche

Feb. 28, 2018—Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.

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Muscular dystrophy clue

Feb. 9, 2018—Vanderbilt investigators have discovered a role for immune system T cells in slowing the decline in skeletal muscle function in patients with Duchenne muscular dystrophy.

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Cell skeleton and the brush border

Jan. 31, 2018—Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.

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Imaging features predict tumor grade

Jan. 29, 2018—Vanderbilt researchers have discovered imaging features associated with increased risk for aggressive meningiomas (tumors of the brain membranes) that could help guide surgical planning and patient counseling.

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Number of minority trainees on rise, but not minority faculty

Jan. 25, 2018—Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty.

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HDL and kidney injury after surgery

Jan. 17, 2018—Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.

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Lighting up iron levels

Jan. 11, 2018—A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease.

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Asthma study may point to potential new therapeutic approach

Jan. 4, 2018—New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition.

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DNA damage repair: molecular insights

Dec. 5, 2017—Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.

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Lineage tracing in the gut

Nov. 30, 2017—Vanderbilt investigators have developed an algorithm to classify cell types from experimental data, making it possible to understand how organs develop.

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