Skip to main content

NIGMS Archives

Antibiotics with anticancer potential

Feb. 25, 2015—A series of experimental antibiotics may be a good starting point for developing new anticancer drugs.

Read more


‘Stretched’ cells promote cancer

Feb. 19, 2015—Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.

Read more


Gene profile predicts metastasis

Feb. 9, 2015—A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.

Read more


Copper toxicity and Parkinson’s

Feb. 5, 2015—A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

Read more


New clue to a devastating disease

Jan. 28, 2015—New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.

Read more


Immune response depends on force

Jan. 26, 2015—New studies explain how T-cell receptors use force to recognize and protect us against pathogens.

Read more


Enzyme affects tumor metastasis

Jan. 8, 2015—A protein that degrades the “matrix” between cells participates in the development of lung metastases from primary breast cancer in mouse models and may be a good target for breast cancer treatment.

Read more


Atrial disease and hypertension links

Dec. 18, 2014—New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

Read more


Retinal neuron survival in glaucoma

Dec. 16, 2014—Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions.

Read more


New tools to probe manganese biology

Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.

Read more


VU study reveals factor’s new role in cell division, migration

Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.

Read more


Immune cells’ role in hypertension

Oct. 24, 2014—Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

Read more


Page 6 of 12« First...345678910...Last »