Dec. 8, 2016—Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
Nov. 18, 2016—A novel drug that targets the protein RSK blocked aggressive breast cancers from metastasizing in an animal model.
Nov. 17, 2016—Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.
Nov. 10, 2016—Understanding how mutations affect the structure and function of inhibitory neurotransmitter receptors will shed light on the mechanisms underlying some types of epilepsy.
Nov. 3, 2016—Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.
Oct. 21, 2016—Vanderbilt researchers have determined that a previously uncharacterized protein responds to DNA replication stress and has an essential role in maintaining the integrity of the genome.
Sep. 26, 2016—Too much dietary zinc increases susceptibility to infection by Clostridium difficile — “C. diff” — the most common cause of hospital-acquired infections.
Sep. 9, 2016—Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers.
Sep. 8, 2016—A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.
Aug. 12, 2016—Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies.
Jul. 14, 2016—New studies of a membrane transporter could explain antibiotic resistance – and lead to novel ways to combat it.
May. 12, 2016—COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.