NIGMS

Vanderbilt researchers have developed a novel algorithm to improve results from proteomic studies. Read More

An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read More

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen. Read More

The factor IRF6 plays important roles in the development of the tongue. Read More

Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies. Read More

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read More

Researchers have found an unusual interaction between a factor that “turns on” protein synthesis and one that produces fatty acids. Read More

Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require. Read More

(iStock) The circadian clocks that control and influence dozens of basic biological processes have an unexpected “snooze button” that helps cells adapt to changes in their environment. A study by Vanderbilt University researchers published online Feb. 17 by the journal Nature provides compelling new evidence that at least some species… Read More

It’s possible to cure Chagas disease – a deadly tropical infection transmitted by “kissing bugs” – in a mouse model. Read More

Structural studies reveal a new framework for understanding a central player in DNA processing. Read More

Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development. Read More

It may be possible to fight hospital-acquired pathogens like Acinetobacter baumannii by targeting the bacterium’s need for the nutrient metal zinc. Read More

The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read More

Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death. Read More

The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells. Read More

Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together. Read More

A transcription factor called LIP is capable of causing one cell to consume another. Read More

A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies. Read More

Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered. Read More