NIDDK
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Adhesion protein optimizes border
Matthew Tyska and colleagues have found that an adhesion protein in the gut is necessary for proper intestinal functioning. Read MoreFeb 15, 2019
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New target for chronic kidney disease
Craig Brooks and colleagues have identified a mechanism of kidney fibrosis progression, suggesting a potential new angle for treating chronic kidney disease. Read MoreJan 31, 2019
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Building a pancreas
Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop. Read MoreJan 17, 2019
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Pain relievers a risk for C. diff?
David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers. Read MoreJan 17, 2019
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Beta cell biomarker findings may speed diabetes research
Researchers at Vanderbilt University Medical Center have identified a biomarker for insulin-producing beta cells. Their finding could lead to improved ways to study and treat diabetes. Read MoreNov 30, 2018
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Green tea and diabetes
A recent study led by Xiao-Ou Shu and colleagues found that green tea drinking was associated with increased risk of type 2 diabetes in Chinese adults, possibly due to the use of pesticides on tea plants--though the researchers call for further study of the exact mechanism. Read MoreNov 30, 2018
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Analyzing single-cell landscapes
Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies. Read MoreNov 30, 2018
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Team’s findings show glutamine metabolism affects T cell signaling
Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read MoreNov 1, 2018
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Targeting diabetic kidney disease
Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease. Read MoreOct 16, 2018
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Insulin accelerant
Reducing nitric oxide helps insulin move more quickly through blood vessels, find David Wasserman and colleagues. Read MoreOct 16, 2018
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Mass spectrometry team earns grant to map body at the cellular level
Biochemistry professor Richard Caprioli, director of the Mass Spectrometry Research Center, and Jeff Spraggins, research assistant professor of biochemistry, and their team will build a platform to molecularly characterize cells. Read MoreSep 28, 2018
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Diabetes drug may prevent liver cancer
A new study by Harvey Murff finds that diabetics who take metformin have lower rates of liver cancer than those who take other diabetes drugs. Read MoreSep 21, 2018
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Investigators find that bile acids reduce cocaine reward
The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction. Read MoreAug 30, 2018
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Toxin floats on lipid rafts
The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read MoreApr 23, 2018
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Disease-fighting antibody production
New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read MoreApr 20, 2018
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Voluntary exercise and energy balance
Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered. Read MoreMar 23, 2018
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Kidney disease imaging
Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read MoreMar 22, 2018
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Peek named to serve on NIDDK Advisory Council
Richard Peek, MD, director of the Vanderbilt Digestive Disease Research Center (VDDRC) and chief of the Division of Gastroenterology, Hepatology and Nutrition, has been appointed to serve on the advisory council of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Read MoreMar 15, 2018
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A new target for neuroblastoma
Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics. Read MoreFeb 14, 2018
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Cognition in rare hormonal disorder
Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read MoreFeb 13, 2018