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genetics

New method reveals how differences in the genetic “instruction booklet” between humans and Neanderthals influenced traits

Oct. 7, 2019—When it comes to our differences from Neanderthals, most of what we know comes from comparing fossils. But fossils can only tell us about bones and not whole living organisms. That’s changing thanks to a new paper from a team of genomics researchers at Vanderbilt, who have developed a first-of-its-kind computational method. Their approach uses...

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Vanderbilt study links gene expression, disease association data

Jul. 27, 2018—An international team of researchers led by Eric Gamazon has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.

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Shared genetics may shape treatment options for certain brain disorders

Jun. 14, 2018—Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.

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New breast cancer targets

May. 4, 2018—A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer.

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Next Discovery Sciences Emerging Scholars Lecture is May 3, featuring Ishmail Abdus-Saboor

Apr. 19, 2018—Ishmail Abdus-Saboor, postdoctoral fellow in the Department of Neuroscience at the University of Pennsylvania, will deliver the School of Medicine's next Discovery Sciences Emerging Scholars Lecture with the topic is "Genetic Interrogation of Neural Circuit Mechanisms for Pain."

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Study spots undiagnosed genetic diseases in EHR

Mar. 15, 2018—Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases.

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Cognition in rare hormonal disorder

Feb. 13, 2018—Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder.

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Personalized drug prescribing program expands, upgrades

Jan. 25, 2018—Vanderbilt University Medical Center (VUMC) has expanded and relaunched genetic testing to predict patient responses to drugs.

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Vanderbilt University School of Medicine to offer new master’s degree in genetic counseling

Dec. 11, 2017—Genetic counseling is one of the fastest growing health professions in the country. Demand for genetic counselors is far outpacing the number of trained specialists, prompting the creation of a new degree program at Vanderbilt University School of Medicine. The Board of Trust recently approved a master of genetic counseling degree, and the first students are expected to enroll for the fall 2019 semester.

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Oxidative stress on the brain

Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.

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New method for tapping vast plant pharmacopeia to make more effective drugs

Apr. 14, 2017—Geneticists have developed an effective new method for identifying the genes that produce the chemicals plants use to protect themselves from predators, which are an important natural drug source.

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Mutation raises heart block risk

Mar. 3, 2017—A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care.

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