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genetics

Amish aid search for Alzheimer’s genes

Oct. 11, 2012—An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.

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Biology, race and politics explored in upcoming Chancellor’s Lecture

Oct. 10, 2012—Is race a biological category written in our genes? Or are genomic scientists and biomedical researchers mistakenly using race to explain away health disparities among different population groups? Dorothy Roberts, the Penn Integrates Knowledge Professor at the University of Pennsylvania, will explore this issue in an upcoming Chancellor’s Lecture at Vanderbilt University.

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Neuronal subtypes in genetic disorder

Sep. 6, 2012—Inhibitory neurons that connect and regulate signaling in the brain (interneurons) may contribute to epilepsy and autism in patients with tuberous sclerosis complex.

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What do beer, dogs and cats have in common? A tale of microbial domestication

Jul. 12, 2012—Study maps the genetic changes involved in the domestication of Aspergillus oryzae, one of the fungi used to make sake, soy sauce and miso.

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Vanderbilt identifies genes linked to breast cancer chemo resistance

Jun. 11, 2012—A study led by Vanderbilt-Ingram Cancer Center investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn’t effective against some tumors and suggests new therapy options for patients with specific subtypes of breast cancer.

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Common genetic signals for atrial fibrillation decoded

Jun. 8, 2012—An international study co-led by researchers at Vanderbilt University has uncovered six new “susceptibility loci,” chromosomal regions located in or near genes that may play a role in atrial fibrillation, the most commonly diagnosed heart condition.

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New clue to ADHD

May. 15, 2012—A rare genetic change adds support to the idea that altered dopamine signaling is a key risk factor for ADHD.

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Vanderbilt researchers help reveal complex role of genes in autism

Apr. 4, 2012—Mutations in hundreds of genes involved in wiring the brain may contribute to the development of autism spectrum disorders (ASD).

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New York Times: Study says DNA’s power to predict illness is limited

Apr. 3, 2012—Vanderbilt University is already doing genetic analyses of patients to help in developing a shortlist of effective drugs, says Dr. William Schaffner, chairman of the department of preventive medicine at its medical school.

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Vanderbilt cancer investigators win two national GE cancer research grants

Mar. 28, 2012—Vanderbilt-Ingram Cancer Center investigators have won two of the five global innovation grants awarded by the “GE Healthymagination Cancer Challenge.”

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Implications of prenatal testing examined at Grand Rounds event April 13

Mar. 22, 2012—It is now possible to receive a noninvasive prenatal test for Down syndrome that can be administered at 10 weeks of gestation and is reportedly 99 percent accurate. As technology advances and allows for genetic tests, such as MaterniT21, to be developed, what ethical considerations arise? This topic will be explored at “Crossroads of Technology...

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Investigators seek clues to paradox of atrial fibrillation risk

Feb. 17, 2012—Vanderbilt researchers are seeking genetic clues to explain why risk factors for AF are more prevalent in African-Americans but their incidence of the disease is lower than European-Americans.

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