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genetics

Researchers chart new informatics path in tracking disease risk

Feb. 23, 2017—In a study in Circulation: Cardiovascular Genetics, Vanderbilt University’s Jonathan Mosley, M.D., Ph.D., and colleagues use genetic correlation to hitch together two unrelated sets of data, one from a longstanding epidemiological cohort and the other from electronic health records.

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Culprits in genetic epilepsies

Oct. 11, 2016—Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy.

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Neanderthal DNA has subtle but significant impact on human traits

Feb. 11, 2016—The first study that directly compares Neanderthal DNA in the genomes of a significant population of adults of European ancestry with their clinical records confirms that this archaic genetic legacy has a subtle but significant impact on modern human biology.

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Vanderbilt study raises questions about reporting incidental genetic findings

Jan. 5, 2016—A genetic test that suggests a patient may be at increased risk for potentially fatal heart rhythms is very often not as ominous as it sounds.

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New online tool created to tackle complications of pregnancy and childbirth

Nov. 11, 2015—An interdisciplinary team of biologists and medical researchers have created a new platform, which they call GEneSTATION specifically designed to leverage the growing knowledge of human genomics and evolution to advance scientific understanding of human pregnancy and translate it into new treatments for the problems that occur when this complex process goes awry.

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A “CRISPR” way to study disease

Jun. 11, 2015—Using revolutionary CRISPR technology, Vanderbilt investigators have developed a fast and simple method to simultaneously turn off multiple genes in order to study complex diseases.

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VUCast Extra: One mom’s race for a cure for son’s rare disorder

Apr. 7, 2015—It’s a story of love and determination and a debilitating lifelong disorder. A son’s rare genetic disease has led his mom to become a scientist at Vanderbilt University. Watch this VUCast Extra and a mom’s race against time.

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New certification focuses on genetics nursing

Feb. 5, 2015—A nurse practitioner at the Vanderbilt Hereditary Cancer clinic is expected to be one of the first nurses in the country to receive a newly created certification in Advanced Genetics Nursing from the American Nurses Credentialing Center (ANCC).

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New data mining method reveals cancer-driving genes

Jan. 22, 2015—Prospecting for genes that might be implicated in cancer, a Vanderbilt University Medical Center research team has struck pay dirt.

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E-records shed light on drug response

Mar. 31, 2014—Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.

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Study links stem cell gene to prostate cancer susceptibility

Mar. 27, 2014—A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found.

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Web tool speeds pulmonary hypertension discovery

Mar. 5, 2014—The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

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