Ishmail Abdus-Saboor, postdoctoral fellow in the Department of Neuroscience at the University of Pennsylvania, will deliver the School of Medicine’s next Discovery Sciences Emerging Scholars Lecture with the topic is “Genetic Interrogation of Neural Circuit Mechanisms for Pain.”
The lecture is Thursday, May 3, at 4 p.m. in 512 Light Hall.
The nervous system is exquisitely tuned to mount the appropriate behavioral response to somatosensory stimuli ranging from a gentle caress to a harsh mechanical insult. How our nervous systems encode this information, from the level of sensory neuron activation in the skin up toward the central nervous system—in both normal and diseased states—remains enigmatic. Abdus-Saboor’s lab is working to uncover the mechanisms governing sensory encoding of touch, itch and pain.
Using optogenetics, quantitative analysis of animal behavior, and in vivo calcium imaging, the team has (1) determined how a population of pain-sensing neurons has unique morphological and physiological outputs depending upon body location, and (2) developed a new behavioral platform using high-speed videography, statistics and machine learning to distinguish between innocuous versus painful behavior responses.
The Discovery Sciences Emerging Scholars lecture series features young scientists making notable discoveries as postdoctoral fellows or early career faculty.
Contact: Stephen Doster, (615) 936-3883