Genetics
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Genes + culture: Exploring how our first language is echoed in our genes
A person’s native language is often referred to as their “mother tongue.” But does a first language always come from your mother? In a new study conducted by Associate Professor of Biological Sciences Nicole Creanza, postdoctoral student Yakov Pichkar,... Read MoreNov 21, 2024
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Evolutionary biologists determine that culture shapes genetics within, not just between, populations
Nicole Creanza and Yakov Pichkar explore whether subtle cultural differences within a language mirror genetic structure within a population. The answer: Even small cultural differences like dialect can influence the spread of people and genes. Read MoreJun 29, 2023
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Vanderbilt, VUMC investigators garner $1.2M Keck Foundation grant for groundbreaking genetic research
In a collaborative effort between Vanderbilt University and VUMC, Chuck Sanders and Roy Zent have secured a $1.2 million grant from the W. M. Keck Foundation for their innovative project, "Genetic Intolerance Patterns as a Treasure Map to Genes that Define Us as Human." The funding will bolster their study of little-known yet crucial proteins, potentially revolutionizing our understanding of human biology and disease. Read MoreJun 26, 2023
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Vanderbilt biologists discover genetic pathways linking the immune and circulatory systems of mosquitoes during infection
Julián F. Hillyer, professor of biological sciences, and his research team discovered how mosquito immune and circulatory systems are related. This work may lead to the development of novel strategies that protect beneficial insects or harm detrimental ones. Read MoreSep 7, 2022
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Jeffery working with VU, VUMC and VA on substance use disorder prediction technology
Alvin Jeffery awarded $1.5M from the National Institute on Drug Abuse to develop artificial intelligence to predict substance use disorder through genetic information. Jeffery is the only nursing research faculty member with a dual VA appointment. Read MoreSep 1, 2022
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High blood pressure genes improve heart surgery survival in children
Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery. Read MoreMar 24, 2022
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Literature researchers identify attitudes toward genetics across 100 years of film and television
Science’s influence on pop culture is undeniable, and the reverse is equally important. Research led by Jay Clayton, the first literature professor to ever receive funding from the NIH, shows that films portray genetic science as risky far more often than television shows. Read MoreFeb 28, 2022
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VUMC team discovers new genetic disease
Researchers at Vanderbilt University Medical Center have discovered a new genetic disease that causes a severe form of neurogenic orthostatic hypotension, a rapid drop in blood pressure upon standing that can cause fainting. Read MoreJun 3, 2021
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New tool to probe genetic mechanisms of disease
Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases. Read MoreOct 22, 2020
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Vanderbilt researchers develop publicly available COVID-19 animal susceptibility prediction tool; suggests increased risk to horses
All-remote collaboration results in free animal susceptibility tool to help prioritize research and closer examination of at-risk species. Read MoreOct 6, 2020
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International collaboration with Vanderbilt scientists sheds light on rare exocyst mutations that cause severe developmental disabilities in children
Mukhtar Ahmed, Christian de Caestecker and Ian Macara, in collaboration with geneticists from Australia and Italy discover novel mutations in the Exocyst, providing new understanding of a critical cellular protein complex. Read MoreSep 14, 2020
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Vanderbilt develops computational method to explore evolution’s influence on preterm birth
The first comprehensive study of how diverse evolutionary forces influence the leading cause of infant mortality is led by Vanderbilt researchers. Read MoreJul 24, 2020
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New method reveals how differences in the genetic “instruction booklet” between humans and Neanderthals influenced traits
When it comes to our differences from Neanderthals, most of what we know comes from comparing fossils. But fossils can only tell us about bones and not whole living organisms. That’s changing thanks to a new paper from a team of genomics researchers at Vanderbilt, who… Read MoreOct 7, 2019
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Vanderbilt study links gene expression, disease association data
An international team of researchers led by Eric Gamazon has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases. Read MoreJul 27, 2018
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Shared genetics may shape treatment options for certain brain disorders
Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting. Read MoreJun 14, 2018
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New breast cancer targets
A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer. Read MoreMay 4, 2018
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Next Discovery Sciences Emerging Scholars Lecture is May 3, featuring Ishmail Abdus-Saboor
Ishmail Abdus-Saboor, postdoctoral fellow in the Department of Neuroscience at the University of Pennsylvania, will deliver the School of Medicine's next Discovery Sciences Emerging Scholars Lecture with the topic is "Genetic Interrogation of Neural Circuit Mechanisms for Pain." Read MoreApr 19, 2018
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Study spots undiagnosed genetic diseases in EHR
Patients diagnosed with heart failure, stroke, infertility and kidney failure could actually be suffering from rare and undiagnosed genetic diseases. Read MoreMar 15, 2018
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Cognition in rare hormonal disorder
Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read MoreFeb 13, 2018
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Personalized drug prescribing program expands, upgrades
Vanderbilt University Medical Center (VUMC) has expanded and relaunched genetic testing to predict patient responses to drugs. Read MoreJan 25, 2018