• Vanderbilt University

    Immune landscape in adrenal cancer

    The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies. Read More

    Dec 14, 2021

  • Vanderbilt University

    Oral microbes and gastric cancer

    Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development. Read More

    Dec 13, 2021

  • Vanderbilt University

    Cell signaling targets in leukemia

    Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read More

    Dec 9, 2021

  • Vanderbilt University

    Prostate cancer treatment regret

    Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity. Read More

    Dec 9, 2021

  • Vanderbilt University

    AI predicts 24-hour hospital discharge

    Vanderbilt researchers used a machine learning algorithm and data from more than 26,000 hospital stays to predict who would and would not be discharged over the next 24 hours. Read More

    Nov 16, 2021

  • conceptual illustration of brain with tangled scribbles running through it

    The power of white matter

    Using a novel analysis of fMRI data, Vanderbilt researchers discovered intriguing patterns of signals in the brain’s white matter, the “conduit” for relaying signals between different brain regions. Read More

    Nov 11, 2021

  • Dividing cancer cell illustration

    The role of polarity in early cancer

    Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered. Read More

    Sep 21, 2021

  • schizophrenia

    Brain circuits in schizophrenia

    Vanderbilt psychiatrists are probing brain circuit hyperactivity implicated in schizophrenia, with the idea that normalizing the hyperactivity may improve cognitive processes. Read More

    Sep 20, 2021

  • African American woman in pink crossing her hands over her breast

    Structural variants in breast cancer risk genes

    Vanderbilt epidemiologists conducted in-depth whole genome sequencing of breast cancer risk genes in Black women, who die at higher rates and have more aggressive disease, to discover mutations that may improve testing and treatment selection. Read More

    Sep 16, 2021

  • Human kidney cross section on scientific background. 3d illustration

    ‘Pre-conditioning’ restores immune tolerance

    A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered. Read More

    Sep 16, 2021

  • Vanderbilt University

    Using billing codes to count cancers

    The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention. Read More

    Sep 2, 2021

  • illustration of cholesterol blockage

    Potential protection from atherosclerosis

    Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read More

    Aug 19, 2021

  • Vanderbilt University

    Vitamin D impact on disease biomarkers

    In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease. Read More

    Aug 10, 2021

  • conceptual illustration of brain with tangled scribbles running through it

    Sudden death from deep in the brain?

    Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read More

    Aug 9, 2021

  • Motor protein linked to intestinal cell differentiation

    Motor protein linked to intestinal cell differentiation

    The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read More

    Aug 5, 2021

  • Human kidney cross section on scientific background. 3d illustration

    Gene expression in diabetic nephropathy

    Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read More

    Aug 5, 2021

  • A Korean woman with cancer is meeting with her doctor. Chemotherapy treatment is going well. The patient is smiling at her doctor as he shares with her positive news. (A Korean woman with cancer is meeting with her doctor. Chemotherapy treatment is go

    Prediction models for breast cancer

    Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read More

    Jul 27, 2021

  • close up of mans arm as he receives chemotherapy infusion

    Mood and cognition after chemotherapy

    Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read More

    Jul 26, 2021


    Influenza network sizes up COVID

    Hospital data from a CDC network that monitors influenza revealed that adults hospitalized for COVID-19 in the early months of the pandemic were 20x more likely to die compared to hospitalized influenza patients. Read More

    Jul 22, 2021

  • microscope

    Establishing HIV care in Tennessee

    Vanderbilt researchers find that heterosexually active Black males are the least likely to establish HIV care within one month of diagnosis and suggest that targeted interventions focus on this population. Read More

    Jul 13, 2021