• Old fashioned keys on wooden background

    A key to calcium signaling

    Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles. Read More

    Feb 11, 2020

  • Yellow measuring tape, isolated on white background

    Imaging breast cancer cell size

    A noninvasive MRI approach assesses breast tumor cell size and could be a useful way to evaluate early response to neoadjuvant therapy. Read More

    Feb 10, 2020

  • Helicobacter Pylori bacterium, medical illustration pathogenic microorganism in human stomach

    Powering H. pylori pathogenesis

    Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read More

    Feb 6, 2020

  • Genomic analysis visualization. Dna genomes sequencing, deoxyribonucleic acid genetic map and genome sequence analyse. Bioinformatics forensics data or dna radiographic testing vector concept (Genomic analysis visualization

    New tool probes gene regulation

    Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read More

    Feb 6, 2020

  • Closeup of a state of the art MRI scanner at a hospital with retractable bed.

    Imaging nerve regeneration

    Diffusion MRI may provide a noninvasive approach to assess nerve regeneration and distinguish successful from unsuccessful repairs earlier. Read More

    Jan 28, 2020

  • illustration of narrowing in artery showing reduced blood flow

    A new contributor to atherosclerosis

    Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis. Read More

    Jan 27, 2020

  • close up of medium skin toned woman's eye with hazel colored iris

    Insights on diabetic retinopathy

    A drug that targets multiple pathogenic steps in diabetic retinopathy may be an ideal therapeutic strategy for the disease, Vanderbilt researchers report. Read More

    Jan 23, 2020

  • Asian senior woman with cancer holds her granddaughter tightly in her lap. Grandma is wearing a headscarf and smiling. (A beautiful ethnic senior woman with cancer holds her granddaughter tightly in her lap. Grandma is wearing a headscarf

    HDL-cholesterol and breast cancer risk

    Genetic analyses suggest that high circulating HDL-cholesterol levels may increase breast cancer risk — a surprising finding since increased HDL-cholesterol is thought to be healthy. Read More

    Jan 23, 2020

  • Chemical element symbol for zinc from the periodic table

    Zinc uptake by a deadly pathogen

    The increasingly antibiotic-resistant bacterium Acinetobacter baumannii requires zinc to cause infection, and Vanderbilt researchers have identified the zinc uptake system it uses. Read More

    Jan 13, 2020

  • high quality x-ray collection body part and fracture area

    Bone matrix changes during aging

    Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis. Read More

    Jan 10, 2020

  • Vanderbilt University

    Structural views of a C. diff toxin

    D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics. Read More

    Jan 10, 2020

  • Abstract digital sound wave

    Cell fate signaling

    A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy. Read More

    Dec 17, 2019

  • Doctor's hands touching virtual reality diagram of heart on glass screen

    Protein dynamics in the beating heart

    To study the dynamics of structural proteins in the heart, Vanderbilt investigators generated a cellular tool they expect will be useful for screening drugs that affect heart muscle contraction. Read More

    Dec 16, 2019

  • illustration of head dissolving into pixels

    A new anti-seizure target?

    Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy. Read More

    Dec 12, 2019

  • concept of precision medicine or personalized medicine depicting a tablet containing complex health data including x-rays, a laptop, stethoscope and eye shields

    Gregor Mendel would be proud

    A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read More

    Dec 12, 2019

  • discarded clothing size tags

    Getting the goods on obesity

    Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read More

    Nov 19, 2019

  • Cell embryo, Mitosis under microscope. 3D illustration

    Understanding cell division

    Vanderbilt researchers have uncovered another piece in the puzzle of how cells divide — a process that goes awry in cancer cells. Read More

    Nov 18, 2019

  • Networked dots in the shape of a brain

    Blueprint for treating epilepsy

    Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders. Read More

    Nov 14, 2019

  • New mother smiling and holding newborn baby at home

    RSV transmission in the Middle East

    Understanding how RSV is transmitted, which strains dominate and how new strains emerge around the globe will guide better vaccine and anti-viral drug design. Read More

    Nov 14, 2019

  • image of molecule with toxin attached to it

    Endotoxin shock protector

    A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults. Read More

    Nov 5, 2019