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Aliquots

A new regulator of B cell development

Oct. 8, 2019—New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.

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AI maps routes to heart disease

Oct. 7, 2019—Machine learning on unlabeled electronic health record data has shed light on the emergence of cardiovascular disease.

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A step toward gastric cancer

Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.

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A catalog of DNA replication proteins

Oct. 3, 2019—Vanderbilt scientists have identified 593 proteins that are enriched at sites of DNA duplication and chromatin packaging of newly synthesized DNA.

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Treating C. diff: new purpose for an old drug?

Sep. 24, 2019—An inexpensive generic drug once used to prevent gastrointestinal ulcers in people taking daily NSAIDs protects against C. diff infection in mice.

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Tailoring treatment for heart defect

Sep. 23, 2019—By defining the clinical and genetic factors that predict treatment response, Vanderbilt investigators aim to personalize therapy for a common heart complication in preterm infants.

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Microvilli in motion

Sep. 19, 2019—Live cell imaging studies have revealed that microvilli — finger-like protrusions on the surface of epithelial cells — move and collide as they form the brush border.

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Potential prostate cancer biomarkers

Sep. 19, 2019—An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.

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Relational memory in early psychosis

Sep. 10, 2019—Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis.

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Astrocytes and epilepsy

Sep. 9, 2019—A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.

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How salt increases blood pressure

Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

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The plus and minus of microtubules

Sep. 5, 2019—Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.

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