Apr. 15, 2021—Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function.
Apr. 15, 2021—Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities.
Apr. 6, 2021—Unique somatic gene mutations may contribute to racial disparities in the incidence of Wilms tumor — the most common childhood kidney cancer.
Apr. 5, 2021—Vanderbilt researchers have developed a response score using genetic and clinical information to aid prescribing of the widely used pain medication codeine.
Apr. 1, 2021—Team members serving COVID-19 inpatients were more densely connected, interacting far more than their medical ICU counterparts.
Apr. 1, 2021—The discovery of monoclonal antibodies that neutralize Rift Valley Fever Virus — an emerging infection with pandemic potential — lays the foundation for future therapeutic antibody development.
Mar. 23, 2021—Distinct cancer-associated fibroblasts in the prostate tumor microenvironment may influence tumor progression and could point to new therapeutic targets.
Mar. 22, 2021—Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.
Mar. 18, 2021—High-intensity strength training is not more effective than low-intensity training or educational efforts for reducing knee pain in patients with osteoarthritis.
Mar. 18, 2021—In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes.
Mar. 8, 2021—The emergence of pathogenic skin fungi that cause the disease chytridiomycosis is contributing to the global loss of amphibian populations.
Mar. 4, 2021—A probiotic factor given early in life to mice prevented intestinal inflammation in adulthood, providing a rationale for probiotic intervention in individuals at high risk of developing inflammatory bowel disease.