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Aliquots Archives

Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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NSAIDs, genetics and miscarriage

Sep. 20, 2017—A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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Medication safety in the ICU

Sep. 19, 2017—Facilitated reporting of medication-related events in the intensive care unit can provide opportunities for optimizing quality of care and patient safety.

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Inhibiting obesity

Sep. 15, 2017—An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

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Acid reflux cancer link

Sep. 14, 2017—Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

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Heat a trigger for seizures

Sep. 6, 2017—Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.

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Pain and Alzheimer’s disease

Sep. 5, 2017—Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.

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Restricting HIV-1 infection

Sep. 1, 2017—Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment.

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Pancreatic cancer development

Aug. 31, 2017—Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease.

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Oxidative stress on the brain

Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.

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Fatty acids and adenoma risk

Aug. 21, 2017—Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk.

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