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Aliquots Archives

STINGing combination for cancer

Jun. 19, 2017—A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer.

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PET imaging to predict tumor response

Jun. 14, 2017—A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models.

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Repriming replication roadblocks

Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

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Flip side of gut protection

Jun. 9, 2017—Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease.

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Oxidative stress in tumors

May. 18, 2017—Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

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Blood type link to cancer survival

May. 17, 2017—Blood type A was associated with longer ovarian cancer survival in a recent Vanderbilt-led study.

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RSV-HRV viral interference

May. 15, 2017—RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants.

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EETs contribute to insulin sensitivity

May. 11, 2017—Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Clue to recurrent C. diff infection

May. 1, 2017—Children who experience recurrent C. diff infections may have fecal inflammatory markers that could predict risk and improve management of these infections.

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Regulating anxiety in the brain

Apr. 28, 2017—Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

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Polarity protein role in cell survival

Apr. 27, 2017—Vanderbilt investigators have identified an unexpected link between cell survival and the polarized delivery of proteins to the surface of mammary epithelial cells.

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