Health And Medicine
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Worm gene function? Check the map.
New gene expression atlas created for roundworms provides a basis for establishing roles for individual genes in the development of specific cell types. Read MoreMar 3, 2011
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Identification of glaucoma gene brightens future for therapies
Researchers have identified a new candidate gene for the most common form of glaucoma, which runs in families. The findings offer novel insights into glaucoma pathology and could lead to targeted treatment strategies. Read MoreFeb 24, 2011
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Support needed to help nurses tackle substance abuse
Support and treatment, not punishment, are needed to help the 10 to 20 percent of U.S. nurses and nursing students who may have problems with substance abuse and addiction. Read MoreFeb 24, 2011
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Weight’s impact on death risk among Asians revealed
New research about the link between body weight and mortality among Asians, which has not been studied in the past, finds being severely underweight poses a serious threat for this population and that preventing obesity is the top priority moving forward. Read MoreFeb 24, 2011
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Protein ‘scissors’ cut path for cancer
The protein matriptase "cuts" a key component of the prostate tissue barrier and may be involved in prostrate cancer progression, new research finds. Read MoreFeb 22, 2011
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‘Glass ceiling’ exists for women surgeons
Less than a third of surgeons who advance to senior ranks in the U.S. are women, and it's not because they're less qualified or less productive than their male counterparts, new research finds. Read MoreFeb 21, 2011
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New model to test how antidepressants work
A new mouse model offers the ability to better test how selective serotonin reuptake inhibitors (SSRIs) work and could lead to the development of new classes of anti-depressants. Read MoreFeb 18, 2011
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Getting left-right asymmetry right
The protein Nodal has been found to hold the keys to vertebrate asymmetry. Read MoreFeb 17, 2011
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Integrin curbs cancer’s spread
Cell surface molecules called integrins have been found to play an important role when cancer metastasizes. Read MoreFeb 16, 2011
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Fluorine aids gene silencing
Modifying a form of RNAs may improve their efficacy for research and medical uses. Read MoreFeb 15, 2011
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Vanderbilt-pioneered fetal surgery procedure yields positive results
Results of a landmark, seven-year National Institutes of Health-funded trial, Management of Myelomeningocele Study (MOMS), demonstrate clear benefit for babies who undergo fetal surgery to treat spina bifida, the most common birth defect in the central nervous system. Read MoreFeb 9, 2011
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Improving heart patients’ outcomes goal of nursing study
(iStock photo) Vanderbilt University Medical Center is participating in a multi-site, national study to identify the role nurses play in improving outcomes among heart failure patients. Nancy Wells (Vanderbilt) “Heart failure is being recognized as a huge issue in elderly and middle-aged people, and it has a profound effect on… Read MoreFeb 9, 2011
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Seeing serotonin neurons in action
The Vanderbilt MRI Labs Physics / Imaging Department (Anne Rayner / Vanderbilt) Serotonin – a chemical that has roles in multiple brain functions, including mood, sleep and cognition – is manufactured by clusters of brainstem neurons gathered in the raphé nuclei. A reliable, non-invasive imaging method for assessing raphé neuron… Read MoreFeb 9, 2011
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BPA exposure tests in question
The industrial chemical BPA is found in commercial products, such as plastic water bottles. (iStock Photo) The safety of industrial chemicals bisphenol A (BPA) and alkylphenols, which are used in commercial products like plastics, has recently been called into question. Exposure to these chemicals is typically measured… Read MoreFeb 8, 2011
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Bronchiolitis in infants linked to mothers’ asthma, allergies
Tina Hartert, M.D., MPH, left, Kathryn Miller, M.D., MPH, and Yarris Muhammed are on the team studying the links between rhinoviruses and bronchiolitis. (Mary Donaldson / Vanderbilt) An infant’s risk of developing bronchiolitis caused by human rhinoviruses (HRV), aka the common cold, is linked to whether the mother has allergies… Read MoreFeb 7, 2011
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Mapping obesity circuitry in brain
(Photo credit: iStock photo) In the battle of the bulge, one important battalion is a set of brain cells expressing the melanocortin-4 receptor (MC4R). Via signals from the fat-derived hormone leptin, these neurons regulate feeding behavior and fat metabolism in an attempt to regulate body weight. But how leptin influences… Read MoreFeb 7, 2011
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Study tracks how deaf children can develop spoken language
Volunteer Becky Clark reads to a student at the Mama Lere Hearing School at Vanderbilt (Anne Rayner / Vanderbilt) OPTION Schools Inc., in collaboration with the Vanderbilt Department of Hearing and Speech Sciences, is conducting a study looking at how children who are deaf or hard of hearing… Read MoreFeb 4, 2011
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Paraplegia-causing proteins pair up
Peter Hedera, M.D. Hereditary spastic paraplegia (HSP), a group of progressive neurodegenerative disorders that impairs the ability to walk, can be caused by mutations in more than 40 different genes. Despite this genetic heterogeneity, the pathologic features – degeneration of long axons in the spinal cord – are relatively uniform,… Read MoreFeb 4, 2011
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Going underground in search of new drugs
Every few months, chemist Brian Bachmann sheds his white lab coat, collects his flashlight, helmet, surgical gloves and knotted rope, puts on old clothes and hiking boots and heads to a nearby cave. Bachmann, an assistant professor of chemistry at Vanderbilt, has combined his industrial experience in… Read MoreFeb 1, 2011
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Vanderbilt joins consortium to discover and map all Alzheimer’s genes
Jonathan Haines and his colleagues at Vanderbilt are part of a global collaboration to discover and map all genes relating to Alzheimer's disease. (Daniel Dubois / Vanderbilt University) Researchers at Vanderbilt University Medical Center, and across the globe, announced today a multi-national collaboration to discover and map all genes relating… Read MoreFeb 1, 2011