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Author: Leigh MacMillan

EETs contribute to insulin sensitivity

May. 11, 2017—Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension.

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Discovery Lecturer Kandel tackles age-related memory loss

May. 11, 2017—Eric Kandel, M.D., who was awarded the Nobel Prize in 2000 for discovering molecular mechanisms of memory storage, told the crowd at last week’s Flexner Discovery Lecture that he has recently become interested in memory in the aging brain.

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Therapeutic targets for diabetes

May. 3, 2017—Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes.

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Regulating anxiety in the brain

Apr. 28, 2017—Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

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Nobel laureate and memory expert Kandel set for next Discovery Lecture

Apr. 27, 2017—Nobel laureate Eric R. Kandel, M.D., renowned for his studies of learning and memory, will give the next Flexner Discovery Lecture on Thursday, May 4.

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Protein structure may aid in treating Alzheimer’s disease

Apr. 27, 2017—A new protein structure may guide the development of Alzheimer's therapeutics.

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A new mode of DNA repair

Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

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Fighting fungal infections

Apr. 3, 2017—A detailed structural and functional analysis of the yeast protein that is the main target of antifungal drugs will help direct efforts to develop better treatments.

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Molecular motors expert Spudich set for next Discovery Lecture

Mar. 30, 2017—James Spudich, Ph.D., renowned for his studies of proteins that function as molecular motors, will deliver the next Flexner Discovery Lecture on Thursday, April 6.

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Blocking neuroblastoma cell growth

Mar. 22, 2017—An inhibitor of cell metabolism may be a good therapeutic target for neuroblastoma, which accounts for about 15 percent of pediatric cancer-related deaths.

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Role for mouth microbes in diabetes?

Mar. 8, 2017—A higher abundance of certain bacterial species in the mouth appears to reduce the risk of type 2 diabetes, Vanderbilt investigators have discovered.

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Antidote for smoke inhalation injury

Mar. 7, 2017—Routine use of hydroxocobalamin should be considered for victims of smoke inhalation, Vanderbilt researchers suggest.

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