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Author: Leigh MacMillan

Evolution of a deadly virus

May. 23, 2018—Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans.

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Shaping reward circuits

May. 18, 2018—Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry.

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Discovery, innovation drive Biomedical Sciences graduates

May. 17, 2018—A highly accomplished group of 83 students earned doctoral degrees in the biomedical sciences from Vanderbilt during the 2017-2018 academic year.

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Putting the brakes on sepsis

May. 9, 2018—An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection.

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Understanding HDL structure

May. 3, 2018—Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function.

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Gene expression in mitral valve disease

Apr. 25, 2018—A protease gene family may be new targets for treating mitral valve disease, which causes blood to flow backwards in the heart.

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Toxin floats on lipid rafts

Apr. 23, 2018—The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells.

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Disease-fighting antibody production

Apr. 20, 2018—New research links nutrient-responsive cellular signaling to the antibody-mediated immune response.

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MIT’s Orr-Weaver wraps up spring Discovery Lecture series April 26

Apr. 19, 2018—The spring Flexner Discovery Lecture series wraps up on Thursday, April 26, with a presentation by Terry Orr-Weaver, PhD, professor of Biology at the Massachusetts Institute of Technology.

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Nobel laureate Kobilka’s talk explores receptor activation

Apr. 12, 2018—Brian Kobilka, MD, who received the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), shared his team’s progress in understanding receptor activation — and how that might guide drug development — at last week’s Flexner Discovery Lecture.

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Aqueous humor, microRNAs and glaucoma

Apr. 10, 2018—New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy.

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Study reveals frogs bouncing back in Panama

Apr. 5, 2018—A new study reports that some Central American frog species are recovering from a deadly fungal epidemic, perhaps because they have better defenses against the pathogen.

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