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Author: Leigh MacMillan

Obesity interventions: ideal dose?

Dec. 21, 2017—The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years.

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Radiation and pulmonary fibrosis

Nov. 15, 2017—To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response.

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Salt, inflammation and hypertension

Nov. 13, 2017—Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension.

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Advanced imaging tools reveal architecture of cell division machinery

Nov. 9, 2017—Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life.

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Pediatric cardiologist Johns thrives in many roles

Nov. 2, 2017—Pediatric cardiologist James Johns, M.D., relishes being a physician who wears many hats.

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Asthma expert Wenzel set for Nov. 9 Discovery Lecture

Nov. 2, 2017—Sally Wenzel, M.D., a global expert on severe asthma, will deliver the next Flexner Discovery Lecture on Thursday, Nov. 9.

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Bioactive lipids and rheumatoid arthritis

Nov. 1, 2017—An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease.

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Disparities in influenza outcomes

Oct. 30, 2017—Neighborhood determinants – represented by census tract data – contribute to the risk of influenza hospitalization and could be used to guide interventions such as vaccinations to high-risk areas.

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New faculty: Erin Calipari, assistant professor of pharmacology

Oct. 23, 2017—Erin Calipari could be described as a code breaker. Using technologies that allow her to probe the activity of single neurons in awake and behaving animals, she is piecing together the neural code that controls motivation and decision-making.

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Calcium intake and colorectal cancer

Oct. 18, 2017—Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

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Researchers find novel mechanism of resistance to anti-cancer drugs

Oct. 17, 2017—Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance.

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New tools to combat kidney fibrosis

Oct. 13, 2017—Vanderbilt investigators have developed a new mouse model of kidney fibrosis, which provides a platform for identifying new targets and treatment strategies.

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