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Author: Leigh MacMillan

Retroviruses expert Bieniasz set for next Discovery Lecture

Mar. 2, 2017—Paul Bieniasz, Ph.D., a pioneer in the study of retroviruses, will deliver the next Flexner Discovery Lecture on Thursday, March 9.

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Investigators seek new way to define cell identity

Mar. 2, 2017—Vanderbilt researchers hope their new method to describe cells will be widely adopted and used to generate a “Who’s Who” database of cell types.

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A target to heal tiny lungs

Feb. 23, 2017—The protein beta-catenin may be a good target for therapies to treat lung disease that is a common complication of preterm birth.

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Improving therapies for GI tumors

Feb. 20, 2017—A signaling protein overexpressed in upper gastrointestinal cancers is an attractive therapeutic target.

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Neurologist Dalmau set for next Discovery Lecture

Feb. 16, 2017—Josep Dalmau, M.D., Ph.D., renowned for his studies of immune disorders affecting the brain and spinal cord, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 23.

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Pathology of septic shock

Feb. 8, 2017—The signaling molecule IL-15 promotes septic shock, a life-threatening condition involving organ injury caused by infection.

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Bacterial signaling systems

Feb. 3, 2017—Vanderbilt researchers have identified a unique example of communication between bacterial signaling systems, which may have relevance for antibiotic resistance.

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Flu vaccine response in older adults

Jan. 25, 2017—High dose flu vaccine boosts the immune response in older adults by increasing activation of certain immune cells.

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Colorectal cancer clues

Jan. 19, 2017—Although cancers arising from different areas of the large intestine are heterogeneous, they appear to use similar important tumorigenic pathways.

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Metastatic pancreatic cancer ‘reprograms’ for malignancy

Jan. 19, 2017—Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

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Midgut neuroendocrine tumor prognosis

Jan. 6, 2017—Vanderbilt investigators recommend that the presence of tumor deposits in the abdomen be included when staging midgut neuroendocrine tumors.

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Plasmin prevents muscle ‘hardening’ after injury: study

Dec. 8, 2016—Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.

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