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Author: Leigh MacMillan

Potential prostate cancer biomarkers

Sep. 19, 2019—An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk.

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Astrocytes and epilepsy

Sep. 9, 2019—A protein with important functions in astrocytes — star-shaped brain support cells — may alter neuronal excitability and contribute to seizure activity, Vanderbilt researchers report.

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How salt increases blood pressure

Sep. 5, 2019—Vanderbilt researchers have discovered that a protein called SGK1 in immune cells is activated by sodium, leading to the development of salt-sensitive hypertension.

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Cancer susceptibility genes

Aug. 26, 2019—Gene variants associated with cancer risk appear to contribute to carcinogenesis by regulating target genes that in turn promote the generation of mutations.

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New prostate cancer treatment concept

Aug. 22, 2019—Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer.

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Host-microbe interactions in the gut

Aug. 13, 2019—Vanderbilt investigators demonstrated that intestinal cells promote beneficial microbe behavior — the findings support developing microbiota-based therapies for intestinal health.

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A probiotic treatment for obesity?

Aug. 8, 2019—Engineered bacteria that produce beneficial compounds — and that could potentially be administered in foods like yogurt — may be a future treatment for obesity and other chronic diseases.

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Cellular engines of wound repair have distinct roles

Aug. 8, 2019—Vanderbilt investigators have now discovered that, in contrast to prevailing dogma, fibroblasts are not all alike; instead, they have distinctive functions following tissue injury.

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Intestinal immune cell interactions

Jul. 30, 2019—Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

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Team’s study reveals details of new DNA repair pathway

Jul. 25, 2019—Investigators have discovered how a DNA repair pathway protein shields sites of damage to avoid mutations and maintain genome integrity.

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Madhur receives Presidential Early Career Award

Jul. 18, 2019—Meena Madhur, MD, PhD, has received a Presidential Early Career Award for Scientists and Engineers.

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Clinical study tests drug that may prevent cancer metastasis

Jul. 8, 2019—A clinical study of a drug that may block cancer metastasis is currently enrolling patients at the Vanderbilt-Ingram Cancer Center.

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