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Author: Leigh MacMillan

Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Cellular calcium handling in diabetes

Sep. 28, 2017—Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

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VU scientists discuss cancer treatments, cellular dynamics

Sep. 28, 2017—A trio of Vanderbilt University scientists described their cutting-edge investigations of cellular dynamics and cancer treatment during last week’s Flexner Discovery Lecture.

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Excess dietary manganese increases risk of staph infection in heart

Sep. 21, 2017—Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).

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NSAIDs, genetics and miscarriage

Sep. 20, 2017—A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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Inhibiting obesity

Sep. 15, 2017—An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

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Trio of Vanderbilt scientists set for Discovery Lecture

Sep. 14, 2017—Three Vanderbilt University scientists on the forefront of research in cellular dynamics and cancer treatment will discuss their cutting-edge investigations during the next Flexner Discovery Lecture on Thursday, Sept. 21.

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Restricting HIV-1 infection

Sep. 1, 2017—Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment.

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Pancreatic cancer development

Aug. 31, 2017—Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease.

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Grants bolster research on rare neurological disorder AHC

Aug. 24, 2017—Kevin Ess, M.D., Ph.D., Gerald M. Fenichel Professor of Neurology, has received two grants from the Alternating Hemiplegia of Childhood Foundation (AHCF).

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Fatty acids and adenoma risk

Aug. 21, 2017—Vanderbilt researchers have found that red blood cell membrane fatty acid content is associated with risk of having colorectal adenomas, with omega-6 fatty acids increasing and omega-3 fatty acids decreasing risk.

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Discovery sheds light on protein key to nerve cells’ myelin sheath

Aug. 17, 2017—Genetic mutations in PMP22 (peripheral myelin protein 22) cause a variety of peripheral neuropathies, underscoring the importance of the protein to a healthy peripheral nervous system. But the precise function of PMP22, a major component of the myelin sheath that surrounds and insulates peripheral nerve cell axons, has been unclear.

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