Leigh MacMillan
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Disease-fighting antibody production
New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read MoreApr 20, 2018
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MIT’s Orr-Weaver wraps up spring Discovery Lecture series April 26
The spring Flexner Discovery Lecture series wraps up on Thursday, April 26, with a presentation by Terry Orr-Weaver, PhD, professor of Biology at the Massachusetts Institute of Technology. Read MoreApr 19, 2018
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Nobel laureate Kobilka’s talk explores receptor activation
Brian Kobilka, MD, who received the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), shared his team’s progress in understanding receptor activation — and how that might guide drug development — at last week’s Flexner Discovery Lecture. Read MoreApr 12, 2018
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Aqueous humor, microRNAs and glaucoma
New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy. Read MoreApr 10, 2018
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Study reveals frogs bouncing back in Panama
A new study reports that some Central American frog species are recovering from a deadly fungal epidemic, perhaps because they have better defenses against the pathogen. Read MoreApr 5, 2018
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Health information technology expert Tang set for Discovery Lecture
Paul Tang, an expert in health information technology, will deliver the next Flexner Discovery Lecture on Thursday, April 12. Read MoreApr 5, 2018
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Lung diseases share molecular signature
Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read MoreApr 5, 2018
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Nobel laureate Kobilka set to deliver Flexner Discovery Lecture on April 5
Brian Kobilka, MD, who shared the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), will deliver the next Flexner Discovery Lecture on April 5. Read MoreMar 29, 2018
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What protein is that?
An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research. Read MoreMar 28, 2018
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Voluntary exercise and energy balance
Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered. Read MoreMar 23, 2018
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Kidney disease imaging
Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read MoreMar 22, 2018
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New imaging approach offers unprecedented views of staph infection
A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state. Read MoreMar 15, 2018
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Botox for the shaky voice
Vanderbilt investigators found that Botox injection into the vocal cords can lead to improved quality of life for patients with voice muscle problems. Read MoreMar 14, 2018
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Brain connections in schizophrenia
Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read MoreMar 9, 2018
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Cancer immunotherapies expert Allison set for Discovery Lecture
James Allison, PhD, whose work led to the development of cancer immunotherapies known as “checkpoint inhibitors,” will deliver the next Flexner Discovery Lecture on Thursday, March 8. Read MoreMar 1, 2018
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Structure of a stem cell niche
Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read MoreFeb 28, 2018
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Cannabis compound reduces seizures
Cannabidiol (CBD) oils reduced seizures in patients with difficult-to-treat epilepsy, Vanderbilt investigators have found. Read MoreFeb 26, 2018
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Sepsis trial ranked No. 1 on critical care website
A clinical trial of an intervention for sepsis in patients in Zambia, led by Vanderbilt investigators, topped the list of 2017 trials featured by the website The Bottom Line. Read MoreFeb 15, 2018
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A new target for neuroblastoma
Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics. Read MoreFeb 14, 2018
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Cognition in rare hormonal disorder
Vanderbilt investigators have conducted the first systematic evaluation of cognitive function in children with a rare genetic disorder. Read MoreFeb 13, 2018