Leigh MacMillan
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Protecting transplanted lungs
Acetaminophen may offer a simple treatment to prevent tissue injury following lung transplant, Vanderbilt researchers have discovered. Read MoreFeb 12, 2018
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Congenital heart disease expert Gelb set for Discovery Lecture
Bruce Gelb, MD, an expert on congenital heart defects, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 8. Read MoreFeb 1, 2018
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Cell skeleton and the brush border
Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read MoreJan 31, 2018
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Imaging features predict tumor grade
Vanderbilt researchers have discovered imaging features associated with increased risk for aggressive meningiomas (tumors of the brain membranes) that could help guide surgical planning and patient counseling. Read MoreJan 29, 2018
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Number of minority trainees on rise, but not minority faculty
Vanderbilt investigators examined the entire training pathway of potential biomedical research faculty and found two key points of loss: during undergraduate education and in transition from postdoctoral fellowship to tenure-track faculty. Read MoreJan 25, 2018
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National report sounds alarm on clinician burnout
A new report issued by the Blue Ridge Academic Health Group calls clinician burnout a “hidden epidemic” and suggests that addressing it should be one of the highest priorities across the healthcare industry. Read MoreJan 25, 2018
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A spicy finding
Vanderbilt researchers have discovered that curcumin — the active ingredient in the spice turmeric — needs to be metabolically activated to exert anti-inflammatory effects. Read MoreJan 16, 2018
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Lighting up iron levels
A new probe enables iron imaging in living animals, providing a unique tool for studying iron’s contributions to health and disease. Read MoreJan 11, 2018
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Asthma study may point to potential new therapeutic approach
New findings from Vanderbilt suggest that blocking the migration of cells involved in asthma may represent a new approach for treating the respiratory condition. Read MoreJan 4, 2018
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Obesity interventions: ideal dose?
The optimal “dose” for behavioral interventions to treat childhood obesity are not clear, Vanderbilt researchers concluded after analyzing 133 clinical trial that occurred over the course of 17 years. Read MoreDec 21, 2017
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Radiation and pulmonary fibrosis
To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response. Read MoreNov 15, 2017
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Salt, inflammation and hypertension
Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read MoreNov 13, 2017
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Advanced imaging tools reveal architecture of cell division machinery
Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life. Read MoreNov 9, 2017
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Pediatric cardiologist Johns thrives in many roles
Pediatric cardiologist James Johns, M.D., relishes being a physician who wears many hats. Read MoreNov 2, 2017
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Asthma expert Wenzel set for Nov. 9 Discovery Lecture
Sally Wenzel, M.D., a global expert on severe asthma, will deliver the next Flexner Discovery Lecture on Thursday, Nov. 9. Read MoreNov 2, 2017
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Bioactive lipids and rheumatoid arthritis
An enzyme that produces bioactive fatty acids has elevated activity in patients with rheumatoid arthritis, supporting further studies to understand its biologic roles in the disease. Read MoreNov 1, 2017
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Disparities in influenza outcomes
Neighborhood determinants – represented by census tract data – contribute to the risk of influenza hospitalization and could be used to guide interventions such as vaccinations to high-risk areas. Read MoreOct 30, 2017
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New faculty: Erin Calipari, assistant professor of pharmacology
Erin Calipari could be described as a code breaker. Using technologies that allow her to probe the activity of single neurons in awake and behaving animals, she is piecing together the neural code that controls motivation and decision-making. Read MoreOct 23, 2017
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Calcium intake and colorectal cancer
Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered. Read MoreOct 18, 2017
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Researchers find novel mechanism of resistance to anti-cancer drugs
Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance. Read MoreOct 17, 2017