Jens Meiler

A recent study from the labs of Lars Plate and Jens Meiler, published in the Proceedings of the National Academy of Sciences of the United States of America, analyzed both selectively responsive and poorly responsive variants of cystic fibrosis and revealed the molecular determinants of drug response. Read More

Jens Meiler, Distinguished Research Professor of Chemistry, was named the principal investigator for the project, in cooperation with 14 investigators across eight institutions. The team will work together to use advanced technology, including computational modeling, AI-driven predictions and structural biology, to develop a groundbreaking vaccine against all alphaviruses that offers long-lasting protection. Read More

Using computer-aided drug design, Heidi Hamm, Craig Lindsley, and Jens Meiler and their labs generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read More

WATCH: Today’s fight against infectious diseases is being waged in the computer lab as much as the wet lab. Using artificial intelligence and machine learning, Vanderbilt researchers and students like School of Engineering undergraduate Karen Pu are expanding the power of computer modeling to identify mutating viruses—and potentially improve vaccines. Read More

A Vanderbilt study suggests that clinicians should take a deeper dive into distinguishing EGFR mutations when prescribing targeted therapies for non-small-cell lung cancers. Read More

Cancer specialists at Vanderbilt University Medical Center, in partnership with biochemists and structural biologists across the Vanderbilt University campus, are taking “personalized” cancer therapy to a new level. Read More

All-remote collaboration results in free animal susceptibility tool to help prioritize research and closer examination of at-risk species. Read More

A Vanderbilt team and their international colleagues characterized for the first time a complex, little-understood cellular receptor type that, when activated, shuts off hunger. Read More

Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression. Read More

It’s been known for some time that the immune system can produce antibodies capable of “neutralizing” HIV, and stopping the AIDS-causing virus dead in its tracks. Read More

Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance. Read More

Vanderbilt researchers have received a five-year, $9 million grant from the National Institutes of Health to design more effective flu vaccines and novel antibody therapies. Read More

With the help of a computer program called “Rosetta,” researchers at Vanderbilt University have “redesigned” an antibody that has increased potency and can neutralize more strains of the AIDS-causing human immunodeficiency virus (HIV) than can any known natural antibody. Read More

Vanderbilt University researchers have received a five-year, $9 million grant from the National Institutes of Health (NIH) to design more effective flu vaccines and novel antibody therapies. Read More

Fifteen faculty members from diverse disciplines have been selected as the first cohort of the Chancellor Faculty Fellows program. Read More

Thanks in part to a computer program named “Rosetta,” Vanderbilt University researchers are closer to understanding how the ubiquitous G protein is activated – a discovery that could lead to the design of more specific and effective drugs. Read More

In the last five years a grassroots faculty collaboration with the University of Leipzig has flowered, making the historic German university one of Vanderbilt's half dozen strategic international partners. Read More

A team of Vanderbilt chemists have designed and successfully synthesized the largest artificial protein using a new approach that greatly expands scientists’ ability to create proteins unknown in nature. Read More

In addition to her high school diploma, Aziza Hart earned an unusual honor this spring – her first scientific paper was published in a new Vanderbilt University journal, Young Scientist. Hart, who graduated from Nashville’s Glencliff High School, spent part of her senior year in a Vanderbilt laboratory, studying… Read More

Researchers have discovered how key proteins are “turned on” and transmit signals inside the cell. The discovery could lead to new, more effective drugs. Read More