Skip to main content

drug discovery Archives

Channel drug restores glucose balance

Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

Read more


Small molecule protects kidney filter

Mar. 19, 2014—A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.

Read more


Fishing for new anti-cancer drugs

Sep. 18, 2013—Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug.

Read more


Institute of Chemical Biology to celebrate 10th anniversary

Feb. 28, 2013—Top chemists from around the country will be on hand March 12 to celebrate the 10th anniversary of the Vanderbilt Institute of Chemical Biology (VICB), a brave experiment that helped jumpstart the University’s robust drug discovery initiative.

Read more


Structural snapshot hints at new influenza approach

Feb. 21, 2013—A careful look at how the body’s natural defenses disarm virulent strains of influenza hints at the possibility of a way to fight the flu.

Read more


New tool for mining bacterial genome for novel drugs

Jan. 25, 2013—Vanderbilt biochemists have discovered that the process bacteria undergo when they become drug resistant can act as a powerful tool for drug discovery.

Read more


Caving for Cures project gains museum limelight

Sep. 17, 2012—If you drop by the American Museum of Natural History the next time you visit New York, there is a good chance that you will see an exhibit highlighting Vanderbilt chemist Brian Bachmann’s "caving for drugs" research.

Read more


Insights for neuroscience drug discovery

Jul. 17, 2012—When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects.

Read more


New tool hooks heart failure drugs

Apr. 6, 2012—A new screening tool – using glowing fish embryos – could identify therapeutics for myocardial hypertrophy and heart failure.

Read more


Vanderbilt expanding research enterprise into Williamson County

Mar. 9, 2012—With the addition of a new 18,000-square-foot laboratory to be located within the Cool Springs Life Sciences Center, Vanderbilt University is expanding its research enterprise into Williamson County.

Read more


Fishing for heart attack repair tools

Jan. 5, 2012—Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool: zebrafish. The researchers visually screened...

Read more


New schizophrenia drug candidates entering prep for first-in-human testing

Dec. 15, 2011—The progression of new drug candidates for schizophrenia with partner Janssen Pharmaceutica is the latest evidence that a new collaborative model for drug discovery pioneered at Vanderbilt may help identify and develop innovative candidate drugs for treatment of major brain disorders.

Read more


Page 3 of 41234