Aliquots
-
Brain blood vessel response to hypoxia
The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered. Read MoreOct 15, 2020
-
Early steps in reovirus replication
Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read MoreOct 6, 2020
-
Clue to diabetic kidney disease
Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read MoreOct 5, 2020
-
Pinpointing brain changes in psychosis
Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read MoreOct 1, 2020
-
Genes spell penicillin allergy risk
Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read MoreOct 1, 2020
-
Rational vaccine design
Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development. Read MoreSep 22, 2020
-
Throwing weight around on the internet
What users mention in online weight loss forum tracks with how much weight they lose. Read MoreSep 21, 2020
-
Probing pathogen antibiotic resistance
Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics. Read MoreSep 17, 2020
-
New predictors of prostate cancer risk
An international group of researchers including Vanderbilt epidemiologists has identified new DNA methylation biomarkers associated with prostate cancer risk. Read MoreSep 17, 2020
-
Fibroids and birth outcomes
Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read MoreSep 8, 2020
-
Possible key to COVID-19 infectivity
New findings demonstrate how genetic variations in the receptor that binds SARS-CoV-2 impact virus recognition and infectivity and offer insights to COVID-19 susceptibility and treatment. Read MoreSep 7, 2020
-
New clue to Alzheimer’s disease
Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read MoreSep 3, 2020
-
Assembling cell power plant machinery
Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production. Read MoreSep 3, 2020
-
Blocking tumor ‘signals’ and ‘fuel’
Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read MoreAug 25, 2020
-
Land of plenty (of opioids)
Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read MoreAug 24, 2020
-
Salt, immune cells and hypertension
Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read MoreAug 20, 2020
-
A “torque” for tumor blood vessels
Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read MoreAug 20, 2020
-
Risk marker for repeat sinus surgery
An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery. Read MoreAug 11, 2020
-
A step toward cancer prevention
A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention. Read MoreAug 10, 2020
-
ID of ‘stomach flu’ culprit
Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read MoreAug 6, 2020