Aliquots
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Throwing weight around on the internet
What users mention in online weight loss forum tracks with how much weight they lose. Read MoreSep 21, 2020
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Probing pathogen antibiotic resistance
Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics. Read MoreSep 17, 2020
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New predictors of prostate cancer risk
An international group of researchers including Vanderbilt epidemiologists has identified new DNA methylation biomarkers associated with prostate cancer risk. Read MoreSep 17, 2020
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Fibroids and birth outcomes
Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read MoreSep 8, 2020
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Possible key to COVID-19 infectivity
New findings demonstrate how genetic variations in the receptor that binds SARS-CoV-2 impact virus recognition and infectivity and offer insights to COVID-19 susceptibility and treatment. Read MoreSep 7, 2020
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New clue to Alzheimer’s disease
Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read MoreSep 3, 2020
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Assembling cell power plant machinery
Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production. Read MoreSep 3, 2020
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Blocking tumor ‘signals’ and ‘fuel’
Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read MoreAug 25, 2020
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Land of plenty (of opioids)
Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read MoreAug 24, 2020
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Salt, immune cells and hypertension
Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read MoreAug 20, 2020
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A “torque” for tumor blood vessels
Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read MoreAug 20, 2020
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Risk marker for repeat sinus surgery
An inflammatory factor in mucus could be a biomarker of treatment-resistant chronic sinusitis used to determine which patients are at risk for repeat sinus surgery. Read MoreAug 11, 2020
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A step toward cancer prevention
A computational technique that combines the effect of multiple genomic variants has the potential to identify high-risk individuals for cancer prevention. Read MoreAug 10, 2020
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ID of ‘stomach flu’ culprit
Identifying the norovirus genotypes associated with more severe infections in children could guide strain selection for candidate norovirus vaccines. Read MoreAug 6, 2020
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The importance of estrogen cycles
Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer. Read MoreAug 6, 2020
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Post-transplant complication
Vanderbilt researchers conducted the largest analysis to date of a heart complication in children following stem cell transplant. The findings may help guide screening practices to improve outcomes. Read MoreJul 28, 2020
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Soy food, metabolism and the microbiome
Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered. Read MoreJul 27, 2020
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Stomach bug hit-and-run
The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read MoreJul 23, 2020
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Cellular antiviral defenses
A cellular RNA quality control mechanism was known to restrict replication of RNA viruses. Vanderbilt researchers have discovered it is also antiviral against DNA viruses. Read MoreJul 23, 2020
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New tools to study bioactive lipids
Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction. Read MoreJul 14, 2020