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Health and Medicine

A new target for lung cancer

Aug. 17, 2018—Xiangming Ji, Pierre Massion and colleagues have discovered that blocking the transporter protein xCT could slow the progression of non-small cell lung cancer.

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Risk factors for faulty rhythms

Aug. 17, 2018—Prince Kannankeril and colleagues explored clinical and genetic factors associated with atrial tachycardia after congenital heart disease surgery in infants younger than 1 year old.

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Study finds behavioral changes insufficient at preventing early childhood obesity

Aug. 9, 2018—New research by Shari Barkin shows that improving nutrition and increasing opportunities to be more active were insufficient in achieving sustained reduction in childhood obesity in poor neighborhoods.

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Study to explore how rising medication costs impact elderly

Aug. 9, 2018—A team led by Stacie Dusetzina has received a grant to determine whether rising drug prices and out-of-pocket expenses are causing older Americans enrolled in Medicare Part D to delay or never fill their prescriptions.

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Repairs in the basement membrane

Aug. 9, 2018—New research by Andrea Page-McCaw shows that a membrane that wraps around most animal tissues can heal within 24 hours, but does leave a scar.

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Genetic balancing act

Aug. 9, 2018—David Cortez and colleagues have found that a protein called RADX helps modulate a protein called RAD51 in order to make sure exactly the correct amount of DNA repair occurs.

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Poster session Friday will feature work on next-gen vaccines

Aug. 6, 2018—The computer-aided design and engineering of antibodies and vaccine candidates that can neutralize viral scourges like influenza and Ebola will be the topic of an Aug. 17 poster session presented by the Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center.

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Enzyme helps build motor that drives neuron death

Aug. 6, 2018—The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system.

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Vanderbilt study links gene expression, disease association data

Jul. 27, 2018—An international team of researchers led by Eric Gamazon has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases.

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Understanding deaths from post-surgical complications

Jul. 20, 2018—Robert Freundlich and colleagues analyzed records for nearly 1.2 million patients and found that, among patients who died within 30 days of surgery, one in five had a complication independently associated with mortality.

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Fueling the MATE transporter

Jul. 20, 2018—In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs.

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Novel insights on “leaky” gut

Jul. 20, 2018—Disruption of the integrity of the intestinal lining or epithelium contributes to a “leaky” gut and is a common feature of patients with inflammatory bowel disease. Yash Choksi, Christopher Williams and colleagues found that low levels of a certain protein exacerbated the condition.

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