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Health and Medicine

Probing the pathology of impaired cognition

Oct. 26, 2018—A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies

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Grant enhances study of new chemotherapy targets

Oct. 19, 2018—Vanderbilt chemists have been awarded $7.2 million over the next five years from the National Cancer Institute to lead an initiative to better understand how a combination chemotherapy for breast cancer targets DNA.

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Targeting diabetic kidney disease

Oct. 16, 2018—Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease.

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Asthma’s androgen connection

Oct. 16, 2018—New findings by Dawn Newcomb and colleagues suggest an explanation for why women are more prone to asthma than men.

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Cellular stress defense

Oct. 16, 2018—Research led by Sanjay Mishra, and colleagues suggests modular sHSP architecture contributes to the ability of heat-protective proteins to serve as chaperones for a range of unfolded proteins.

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Insulin accelerant

Oct. 16, 2018—Reducing nitric oxide helps insulin move more quickly through blood vessels, find David Wasserman and colleagues.

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Bradley Malin elected to National Academy of Medicine

Oct. 16, 2018—Bradley Malin, professor of biomedical informatics, biostatistics and computer science, is among 85 newly elected members of the National Academy of Medicine.

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Novel genetic study sheds new light on risk of heart attack

Oct. 11, 2018—Loss of a protein that regulates mitochondrial function can greatly increase the risk of a heart attack, report Eric Gamazon, Sandra Zinkel and graduate students Christie Salisbury-Ruf and Clinton Bertram in new research.

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Team’s study reveals hidden lives of medical biomarkers

Oct. 11, 2018—The hidden lives of medical biomarkers are the focus of a recent study in Nature Communications by Jonathan Mosley.

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Fat tissue’s “iron sink”

Oct. 4, 2018—New research by Alyssa Hasty and colleagues shows that a certain immune cell can absorb excess iron that can compromise healthy fat tissue.

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Stretch, inflammation and hypertension

Oct. 4, 2018—New research by David Harrison and colleagues sheds light on how changes in mechanical forces in the aorta enhance immune cell activation thus promoting hypertension.

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Cytokine-cognition connection

Oct. 4, 2018—Erin Calipari and colleagues have shown that peripheral administration of a neuroprotective cytokine may improve dopamine signaling problems associated with certain psychiatric disorders.

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