Health And Medicine
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Eleven Vanderbilt scientists among world’s ‘highly cited’ researchers
Eleven current Vanderbilt University faculty members, 10 of whom are investigators at Vanderbilt University Medical Center, are included in the 2024 list of “Highly Cited Researchers” around the world whose papers have been cited most frequently by other scientists. Read MoreDec 19, 2024
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First successful clinical trial of VU319 brings Alzheimer’s treatment one step closer
Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read MoreDec 19, 2024
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Vanderbilt researchers find evidence that the hunger hormone leptin can direct neural development in a leptin receptor–independent manner
Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Read MoreDec 5, 2024
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Research Snapshot: Spectroscopy and AI method provide unique window into protein structure and mechanism of action
The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological blueprint that couples experimental double electron–electron resonance spectroscopy with an AI approach to help describe the conformational landscapes of a diverse spectrum of cell membrane transporters. Read MoreDec 4, 2024
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Vanderbilt awarded up to $46M through ARPA-H to develop tools against alphaviruses
Jens Meiler, Distinguished Research Professor of Chemistry, was named the principal investigator for the project, in cooperation with 14 investigators across eight institutions. The team will work together to use advanced technology, including computational modeling, AI-driven predictions and structural biology, to develop a groundbreaking vaccine against all alphaviruses that offers long-lasting protection. Read MoreDec 2, 2024
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Analyzing police shootings, public safety, and policy
A series of three recently published studies have provided the first nationally comprehensive analysis of shootings by law enforcement officers that injured or killed people in the U.S. Led by Julie Ward, assistant professor of medicine, health, and so... Read MoreNov 22, 2024
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Genes + culture: Exploring how our first language is echoed in our genes
A person’s native language is often referred to as their “mother tongue.” But does a first language always come from your mother? In a new study conducted by Associate Professor of Biological Sciences Nicole Creanza, postdoctoral student Yakov Pichkar,... Read MoreNov 21, 2024
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New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
Yi Ren’s most recent paper, published in eLife, describes the structure of a protein complex involved in mRNA export that sheds light on the underlying molecular mechanism of mRNA export and the role it plays during infection by herpes viruses. Read MoreNov 21, 2024
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Researchers develop robotic sensory cilia that monitor internal biomarkers to detect and assess airway diseases
Vanderbilt engineering professor Xiaoguang Dong is leading a team of researchers that has developed a system of artificial cilia capable of monitoring mucus conditions in human airways to better detect infection, airway obstruction, or the severity of diseases like cystic fibrosis, chronic obstructive pulmonary diseases and lung cancer. Read MoreNov 7, 2024
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New study sheds light on seasonality in mood disorders
A recent study conducted by Vanderbilt chemistry professors Sandy Rosenthal and Oleg Kovtun found that people experiencing depressed states had lower daytime activity, and people’s daytime activity increased with longer days and more sun exposure. Read MoreOct 31, 2024
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Drug discovery efforts continue in latest chemical chronicle from the Warren Center for Neuroscience Drug Discovery
Led by Craig W. Lindsley, Vanderbilt drug discovery experts set out to develop a backup drug candidate to improve memory loss in people with Alzheimer’s disease. Read MoreOct 31, 2024
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Peter Embí elected to National Academy of Medicine
Peter Embí, professor and chair of the Department of Biomedical Informatics, is among 100 newly elected members of the National Academy of Medicine, the organization announced this week. Read MoreOct 30, 2024
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Vanderbilt receives award from ARPA-H to focus on improving mental health chatbots
A team at Vanderbilt University Medical Center will address the concerns and hopes surrounding health-related AI chatbots with the aid of a two-year funding award of up to $7.3 million from the Advanced Research Projects Agency for Health (ARPA-H). Read MoreOct 16, 2024
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Passion, Perseverance and Synapses: Neuroscientist Richard Sando receives prestigious NIH New Innovator Award
In 2024 the National Institutes of Health awarded Sando a New Innovator Award, part of their High-Risk, High-Reward Research program. This award, which provides $1,500,000 over five years, supports early-career scientists proposing innovative and impactful research that might not get funded in the traditional peer-review process due to its inherent risk. Read MoreOct 11, 2024
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New technology could significantly advance genomic analysis and precision medicine
A team of Vanderbilt researchers has developed a novel tool in the detection and analysis of structural variants in human genomes that could potentially transform genomic analysis and precision medicine. Read MoreOct 10, 2024
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New study finds that anesthesia inhibits brain’s predictive processing
A new study led by Andre Bastos, assistant professor of psychology, found that animal subjects under general anesthesia were unable to detect moderate and complex surprises. This discovery deepens the understanding about the nature of consciousness and how it arises. Read MoreOct 8, 2024
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Erin Calipari wins Society for Neuroscience 2024 Outstanding Career and Research award
Erin Calipari, director of the Vanderbilt Center for Addiction Research and associate professor of pharmacology and molecular physiology and biophysics, has been recognized with the Society for Neuroscience’s 2024 Jacob P. Waletzky award. Read MoreOct 3, 2024
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Shedding light on a decades-old protein sorting mystery
Christian de Caestecker, a Ph.D. student in the lab of Ian Macara, Louise B. McGavock Professor and chair of the Department of Cell and Developmental Biology, has proposed and validated a mechanism that addresses a decades-old mystery surrounding epithelial cells. Read MoreSep 26, 2024
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Vanderbilt University School of Medicine Basic Sciences adds Carterra’s LSAXT instrument to speed drug and vaccine research and advance patient care
Carterra Inc. and the Vanderbilt University School of Medicine Basic Sciences announced the addition of the Carterra LSAXT label-free interaction analysis platform to the Center for Structural Biology. Vanderbilt and Vanderbilt University Medical Center researchers will be able to discover and characterize large molecules including antibodies. Read MoreSep 26, 2024
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Amanda Linkous advances lung cancer research with Merck Research Laboratories Scientific Engagement and Emerging Discovery Science program
Amanda Linkous, research associate professor of pharmacology, has been awarded a research grant from the Merck Research Laboratories Scientific Engagement and Emerging Discovery Science (SEEDS) program to identify therapeutic intervention points to prevent the colonization and proliferation of small cell lung cancer and non-small cell lung cancer in the lung and brain. Read MoreSep 24, 2024