Health And Medicine
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Vanderbilt biostatisticians launch Cancer-Immu data portal for predicting response to immune checkpoint blockade immunotherapy
A new data portal called Cancer-Immu established by a team of Vanderbilt University Medical Center biostatisticians can help cancer clinicians and researchers predict which patients will respond to immune checkpoint inhibitors. Read MoreJan 14, 2022
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Study of fully vaccinated patients with cancer who had breakthrough COVID-19 shows 13% mortality rate
New research finds that fully vaccinated patients with cancer who had breakthrough COVID-19 infections remained at high risk for hospitalization and death. Read MoreDec 24, 2021
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Study finds pixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stroke prevention, reduced bleeding complications
There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stoke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA. Read MoreDec 21, 2021
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“Atlas” of lung development may aid efforts to heal premature lungs
Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time. Read MoreDec 20, 2021
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Study finds similar success rates with two devices for breathing tube placement
Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA. Read MoreDec 15, 2021
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Gene discoveries give new hope to people who stutter
New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter. Read MoreDec 2, 2021
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New way to bEET insulin resistance
Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered. Read MoreNov 11, 2021
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The challenge of rejection
Minimizing variation in how rejection is diagnosed and creating standardized surveillance protocols may help inform best practices in pediatric heart transplants. Read MoreNov 10, 2021
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VUMC researchers a step closer to broad ebolavirus protection
A combination of two broadly acting monoclonal antibodies isolated by researchers at Vanderbilt University Medical Center protected non-human primates from ebolavirus disease, which causes severe and often-fatal hemorrhagic fever in humans. Read MoreNov 10, 2021
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Study explores concussion recovery by race
Vanderbilt researchers are exploring the outcomes and experiences of Black and White athletes following a sports-related concussion. Read MoreSep 23, 2021
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White matter and schizophrenia
Patients with schizophrenia have functional changes in the white matter of the brain, Vanderbilt researchers have discovered, which may contribute to impaired working memory and processing speed. Read MoreSep 2, 2021
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Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients
Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week. Read MoreSep 2, 2021
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Discovery offers insight for development of cancer therapies targeting mutant p53
The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation. Read MoreSep 2, 2021
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Ask an Expert: Who does the vaccine protect?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, reminds us the reasons to get vaccinated. Read MoreAug 24, 2021
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Ask an Expert: Is data about deaths after vaccination valid?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, explains how signals on deaths after COVID-19 is collected and interpreted. Read MoreAug 24, 2021
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Ask an Expert: What do we know about booster shots?
Thomas Talbot, professor of medicine and chief hospital epidemiologist at Vanderbilt University Medical Center, shares what we know about COVID-19 booster shots. Read MoreAug 24, 2021
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Team isolates antibodies that target alphaviruses
A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that prevent infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus. Read MoreAug 19, 2021
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Study reveals missing link between high-fat diet, microbiota and heart disease
A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science. Read MoreAug 12, 2021
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Sudden death from deep in the brain?
Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read MoreAug 9, 2021
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Study finds genetic factor undermines H. pylori treatment
Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Read MoreAug 4, 2021