Leigh MacMillan
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New player in heart cell growth
Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy. Read MoreApr 6, 2015
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Gene variant, environment can boost RSV severity
A particular genetic mutation combined with an urban environment increases the risk of severe disease in children infected with respiratory syncytial virus (RSV), an international team of investigators has found. Read MoreApr 2, 2015
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Aging insights from budding yeast
The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read MoreApr 2, 2015
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Discovery Lecturer O’Rahilly to explore obesity, insulin resistance
Sir Stephen O’Rahilly, M.D., an expert in metabolic and endocrine diseases, will deliver the next Flexner Discovery Lecture on Thursday, April 2. Read MoreMar 26, 2015
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Antibiotics with anticancer potential
A series of experimental antibiotics may be a good starting point for developing new anticancer drugs. Read MoreFeb 25, 2015
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Contributors to coronavirus ‘fitness’
Understanding the role that host membrane modification plays in coronavirus replication is essential for developing novel approaches to block the viruses that cause SARS and MERS. Read MoreFeb 24, 2015
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‘Stretched’ cells promote cancer
Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts. Read MoreFeb 19, 2015
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Discovery Lecture to explore acculturation’s impact on health
Elena Fuentes-Afflick, M.D., MPH, an expert on the effect of acculturation — adoption of the cultural traits of another group — on health outcomes, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 26. Read MoreFeb 19, 2015
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Kidney disease impacts HDL function
Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read MoreFeb 11, 2015
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Copper toxicity and Parkinson’s
A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper. Read MoreFeb 5, 2015
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Couple’s gift bolsters neonatology training, research
Dupree Hatch, M.D., shrugs off the sleep deprivation from a night taking care of babies in the neonatal intensive care unit and launches into a discussion of his efforts to describe — and reduce — adverse events associated with intubation in the NICU. Read MoreFeb 5, 2015
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Immune response depends on force
New studies explain how T-cell receptors use force to recognize and protect us against pathogens. Read MoreJan 26, 2015
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Awards recognize crucial efforts of research staff
John Allison, Ph.D., Linda Horton and Elizabeth Roof are the recipients of the 2014 Research Staff Awards at Vanderbilt University Medical Center. Read MoreJan 15, 2015
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Genome-editing pioneer next up in Discovery Lecture series
Jennifer Doudna, Ph.D., recipient of a 2015 Breakthrough Prize in Life Sciences, will deliver the next Flexner Discovery Lecture on Thursday, Jan. 8. Read MoreJan 2, 2015
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Atrial disease and hypertension links
New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease. Read MoreDec 18, 2014
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Target for atherosclerosis therapies
A newly identified “atheroprotective” gene is a tool for exploring plaque pathophysiology and may be a good target for therapies to slow atherosclerosis progression. Read MoreDec 17, 2014
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Retinal neuron survival in glaucoma
Understanding how the protein TRPV1 helps neurons survive after glaucoma-related stressors could lead to new therapeutic strategies for glaucoma and other neurodegenerative conditions. Read MoreDec 16, 2014
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Bacterial secretion machinery: 3-D view
New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells. Read MoreDec 11, 2014
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Columbia’s Bakken to deliver Flexner Discovery Lecture
Suzanne Bakken, Ph.D., RN, the Alumni Professor of Nursing and professor of Biomedical Informatics at Columbia University, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 11. Read MoreDec 4, 2014
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Physician-scientist is dream job for Vanderbilt’s Cassat
Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections. Read MoreDec 4, 2014