Leigh MacMillan

Changes in the kidney can limit the blood pressure-lowering effects of thiazide diuretics, a new study reports. Read More

Our tissues are in a constant state of flux — cells are lost and cells are generated, with local signals and stem cells maintaining the balance, said Roel Nusse, Ph.D., during last week’s Flexner Discovery Lecture. Read More

A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing. Read More

Best hospital rankings for cancer do not take into account the fact that cancer reflects many different diseases. Read More

New findings suggest that it might be possible to treat diabetes by regenerating insulin-producing beta cells in the pancreas. Read More

Stuffed animals that pediatric patients bring to the operating room are a reservoir of bacteria that can be effectively sterilized in a household washer/dryer the day before surgery. Read More

Roel Nusse, Ph.D., an expert in the regulation of tissue growth and development by Wnt signaling pathways, will deliver the next Flexner Discovery Lecture on Thursday, April 23. Read More

Vanderbilt researchers have identified a new protein involved in heart cell growth, which could improve understanding of pathologic cardiac hypertrophy. Read More

A particular genetic mutation combined with an urban environment increases the risk of severe disease in children infected with respiratory syncytial virus (RSV), an international team of investigators has found. Read More

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered. Read More

Sir Stephen O’Rahilly, M.D., an expert in metabolic and endocrine diseases, will deliver the next Flexner Discovery Lecture on Thursday, April 2. Read More

A series of experimental antibiotics may be a good starting point for developing new anticancer drugs. Read More

Understanding the role that host membrane modification plays in coronavirus replication is essential for developing novel approaches to block the viruses that cause SARS and MERS. Read More

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts. Read More

Elena Fuentes-Afflick, M.D., MPH, an expert on the effect of acculturation — adoption of the cultural traits of another group — on health outcomes, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 26. Read More

Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read More

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper. Read More

Dupree Hatch, M.D., shrugs off the sleep deprivation from a night taking care of babies in the neonatal intensive care unit and launches into a discussion of his efforts to describe — and reduce — adverse events associated with intubation in the NICU. Read More

New studies explain how T-cell receptors use force to recognize and protect us against pathogens. Read More

John Allison, Ph.D., Linda Horton and Elizabeth Roof are the recipients of the 2014 Research Staff Awards at Vanderbilt University Medical Center. Read More