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Leigh MacMillan

  • Vanderbilt University

    VUMC’s Baganz honored by Society for Neuroscience

    For her contributions to public communication, outreach and education about neuroscience, Nicole Baganz, Ph.D., a postdoctoral fellow in Pharmacology, received the 2015 Next Generation Award from the Society for Neuroscience. Read More

    Nov 12, 2015

  • DNA sequence visualization

    Study helps clarify components of DNA ‘copy machine’

    Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read More

    Nov 12, 2015

  • Vanderbilt University

    Detect and defend against pathogens

    Understanding factors, such as the receptor TLR9, that detect and defend against pathogens may lead to therapeutic approaches that promote an effective immune response to treat infections. Read More

    Nov 4, 2015

  • Vanderbilt University

    Prenatal folic acid and asthma

    The timing of folic acid-containing prescription filling during pregnancy was associated with childhood asthma, according to a new Vanderbilt study. Read More

    Oct 30, 2015

  • Vanderbilt University

    Inflammation, obesity and diabetes

    Vanderbilt study adds to the mounting role for inflammatory signaling in obesity. Read More

    Oct 29, 2015

  • Vanderbilt University

    Biomarker for intestinal tumors

    A new marker could be useful for diagnosing and treating neuroendocrine tumors of the small intestines. Read More

    Oct 21, 2015

  • x-ray of lungs with a suspicious spot highlighted in red

    Potential target for lung cancer therapy

    The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read More

    Oct 5, 2015

  • Vanderbilt University

    Collaboration seeks to develop new therapies for bone, other diseases

    La Jolla Pharmaceutical Co. and Vanderbilt University have signed a research and license agreement covering Vanderbilt’s research program and intellectual property rights related to compounds that block bone morphogenetic protein (BMP) type-I receptors. The compounds have therapeutic potential in a broad range of diseases, including rare genetic disorders. Read More

    Oct 1, 2015

  • conceptual - glowing cell

    Tolerating a transplant

    A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read More

    Oct 1, 2015

  • Vanderbilt University

    Hochmair set for next Discovery Lecture

    The co-creator of the world’s first microelectronic multi-channel cochlear implant — a device that provides sound signals to the brain in deaf individuals — will deliver the next Flexner Discovery Lecture. Read More

    Oct 1, 2015

  • Vanderbilt University

    Nerve cell remodelers

    Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read More

    Sep 18, 2015

  • Vanderbilt University

    Discovery Lecture explores health care cost controls

    “There’s no magic bullet” to control rising health care costs in the United States, health law expert Timothy Jost, J.D., said during last week’s Flexner Discovery Lecture. Read More

    Sep 17, 2015

  • Vanderbilt University

    Immune cells and obesity

    Understanding how macrophage immune cells accumulate in fat tissue and contribute to the pathology of obesity could lead to the development of novel therapeutics for metabolic disorders. Read More

    Sep 8, 2015

  • Vanderbilt University

    Vitamin C protects blood vessel lining

    Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases. Read More

    Sep 4, 2015

  • Vanderbilt University

    Jost set for Sept. 10 Discovery Lecture

    The Flexner Discovery Lecture Series kicks off this fall with a discussion of health care cost control. Timothy Jost, J.D., emeritus professor at the Washington and Lee University School of Law, will speak on Thursday, Sept. 10. Read More

    Sep 3, 2015

  • Vanderbilt University

    Framework for studying cell responses

    Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read More

    Aug 26, 2015

  • Vanderbilt University

    Brain circuitry in psychosis

    Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More

    Aug 21, 2015

  • Vanderbilt University

    New therapeutic target for diabetes

    The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes. Read More

    Aug 20, 2015

  • Vanderbilt University

    VUMC study shifts thinking on how bone fractures heal

    New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal. Read More

    Aug 13, 2015

  • Neurons

    Origins of neuroblastoma

    Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer. Read More

    Aug 12, 2015