Leigh MacMillan

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia. Read More

Russ Altman, M.D., Ph.D., professor of Bioengineering, Genetics and Medicine at Stanford University, posed an intriguing question at last week’s Discovery Lecture: is it possible to predict drug side effects from the 3D-structure of proteins? Read More

Neuroscientist Karl Deisseroth, M.D., Ph.D., renowned for his development of tools that allow scientists to control and map brain circuits, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 22. Read More

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity. Read More

Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery. Read More

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer. Read More

Alvin Powers, M.D., professor of Medicine and Molecular Physiology and Biophysics, has been named to the American Diabetes Association Board of Directors. Read More

Russ Altman, M.D., Ph.D., professor and chair of Bioengineering at Stanford University, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 6. Read More

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity. Read More

Hypertension Clinic members include, from left, Sandy Berryhill, LPN, Lynn Christman, Cheryl Laffer, M.D., Matt Luther, M.D., Fernando Elijovich, M.D., Robert Manning, R.N., and Karen Gore, R.N. (Not pictured: Nancy Brown, M.D., Barb Dotson, R.N., and Mena Mangrum, LPN. The American Society of Hypertension (ASH) has… Read More

A new computational model of the interactions between vocal folds and the air around them could aid in designing new treatments for voice disorders. Read More

Understanding the relationship between the thinning and rupture of fetal membranes and the presence of bacteria could lead to treatment and prevention strategies for premature birth. Read More

Understanding how HIV infection affects immune system B cells may guide strategies for vaccine development. Read More

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes. Read More

Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read More

An association between rigid-compulsive behaviors and gastrointestinal symptoms in autism spectrum disorder may point to a common biological pathway that impacts both the brain and the gut. Read More

Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered. Read More

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies. Read More

The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women. Read More

The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis. Read More