Leigh MacMillan

Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry. Read More

A highly accomplished group of 83 students earned doctoral degrees in the biomedical sciences from Vanderbilt during the 2017-2018 academic year. Read More

An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read More

Structural features of newly formed HDL particles will help guide understanding of “good cholesterol” and its function. Read More

A protease gene family may be new targets for treating mitral valve disease, which causes blood to flow backwards in the heart. Read More

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More

New research links nutrient-responsive cellular signaling to the antibody-mediated immune response. Read More

The spring Flexner Discovery Lecture series wraps up on Thursday, April 26, with a presentation by Terry Orr-Weaver, PhD, professor of Biology at the Massachusetts Institute of Technology. Read More

Brian Kobilka, MD, who received the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), shared his team’s progress in understanding receptor activation — and how that might guide drug development — at last week’s Flexner Discovery Lecture. Read More

New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy. Read More

A new study reports that some Central American frog species are recovering from a deadly fungal epidemic, perhaps because they have better defenses against the pathogen. Read More

Paul Tang, an expert in health information technology, will deliver the next Flexner Discovery Lecture on Thursday, April 12. Read More

Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention. Read More

Brian Kobilka, MD, who shared the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), will deliver the next Flexner Discovery Lecture on April 5. Read More

An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research. Read More

Non-exercise physical activity has a measurable energy expenditure, which goes down when animals engage in voluntary exercise, Vanderbilt researchers have discovered. Read More

Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read More

A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state. Read More

Vanderbilt investigators found that Botox injection into the vocal cords can lead to improved quality of life for patients with voice muscle problems. Read More

Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read More