Research

Vanderbilt has extended its longest ongoing drug discovery agreement with Osaka, Japan-based Ono Pharmaceutical Co., Ltd., a research and development-oriented pharmaceutical company that is committed to creating innovative medicines in specific areas, through November 2023. Read More

As the fall 2021 semester concludes, Provost and Vice Chancellor for Academic Affairs C. Cybele Raver expresses confidence in Vanderbilt's potential to set transformative new benchmarks for research, scholarship and creative expression in this message to the university community. In addition, watch the 2021 Research in Review video. Read More

There is strong evidence that the medication apixaban (Eliquis) is preferable to rivaroxaban (Xarelto) for stoke prevention in patients with atrial fibrillation (AF), with both reduced rates of severe bleeding complications as well as strokes, according to study published Dec. 21 in JAMA. Read More

Researchers at Vanderbilt University Medical Center have constructed a single-cell “atlas” of lung development that tracks multiple cell types over time. Read More

by Paul Govern Information based biomedical discovery, in particular the push toward precision medicine, depends on open-ended analysis of de-identified data from patients and research participants on the largest possible scale. Sharing data while controlling the risk of data reidentification under privacy attack is vital to the enterprise. Zhiyu Wan Game theory indicates that only... Read More

Two devices for placing a breathing tube during critical illness had similar success rates for intubation on the first attempt, according to a study published Dec. 8 in JAMA. Read More

The profile of immune-related gene expression and tumor-infiltrating immune cells in adrenocortical cancer suggests targets for new treatment strategies. Read More

Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development. Read More

Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19. Read More

Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read More

Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity. Read More

In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11 with moderate-to-severe asthma, offering a new option to these patients. Read More

New research shows the potential to identify therapeutic directions that could improve outcomes for people who stutter. Read More

In a review of 100 years of research on the sensory systems in whales, Rachel Racicot, research assistant professor of biological sciences, describes advances in the field and key questions that remain. Read More

Researchers in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center have received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition. Read More

Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance of the immune system in the etiology of depression. Read More

Kolouri wins $1M DARPA grant to investigate AI cooperative lifelong learning A Vanderbilt engineering professor is leading part of an international initiative to create advanced artificial intelligence programs that will enable machines to learn progressively over a lifetime and share those experiences with each other. Researchers hope the technology will allow machines to reuse information,... Read More

A study by Vanderbilt researchers sheds light on how current antidepressant drugs work and suggests a new drug target in depression. Read More

A paper by Vanderbilt engineers that explores the scope to scale up the sizes of atomically thin membranes and their potential use in applications relating to energy, microscopy, and electronics is published in the journal Science. Authors Piran R. Kidambi, assistant professor of chemical and biomolecular engineering, Pavan Chaturvedi, postdoctoral scholar in the Department of... Read More

A study led by researchers from Vanderbilt University’s Center for Rehabilitation Engineering and Assistive Technology reveals a breakthrough tool to assess the effect of exoskeletons on injury risk. The tool, called Exo-LiFFT, is an interactive calculator that will help companies looking for ways to overcome workforces struggling with musculoskeletal injuries, missed work, and accelerated retirement... Read More