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Research

Triple-negative breast cancer drug therapy shows promise

Mar. 12, 2020—Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation.

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Baroud receives NSF Early CAREER Award to predict and inform community hazard response

Mar. 11, 2020—Hiba Baroud has received a 2020 NSF Faculty Early CAREER Development grant to boost community resilience and sustainability through a three-pronged project that starts with a better understanding of how people and infrastructures interact during hazards.

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Loss of ‘Jedi’ alters neuron activity

Mar. 10, 2020—This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain.

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Clues to lung injury in preterm babies

Mar. 5, 2020—Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth.

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One-two punch for cancer

Mar. 5, 2020—A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients.

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Study finds certain genetic test not useful in predicting heart disease risk

Feb. 27, 2020—A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk.

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Breast cancer study may help predict treatment response

Feb. 27, 2020—Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat.

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Grant bolsters research on subjective cognitive decline

Feb. 27, 2020—Katherine Gifford, PsyD, MS, assistant professor of Neurology, has been awarded a five-year, $4.3 million research grant from the National Institute on Aging to study what subjective cognitive decline can reveal about underlying pathology.

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Bordenstein honored by Genetics Society of America

Feb. 27, 2020—The Genetics Society of America has recognized Seth Bordenstein, an evolutionary geneticist and microbiologist at Vanderbilt, for an initiative that brings real-world scientific research into middle school, high school and college biology classes.

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Potential new heartburn drug studied at VUMC

Feb. 26, 2020—An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

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Looking through MudPIT for protein interactions

Feb. 25, 2020—The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.

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Team demos breakthrough in analog image processing, Nature reports

Feb. 24, 2020—A research team of Vanderbilt engineers has demonstrated a new ultrathin filter, based on metamaterials, that allows for analog optical image processing.

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