Research
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High blood pressure genes improve heart surgery survival in children
Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery. Read MoreMar 24, 2022
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Rubinov awarded $1.1M to study molecular underpinnings of human brain networks on a large scale
Mikail Rubinov, assistant professor of biomedical engineering, computer science, psychiatry and psychology, has been awarded a four-year, $1.1 million grant from the National Institute of Mental Health to better understand the development and organization of brain networks, as well as their change in development and aging. Rubinov and his collaborators will link aspects of gene expression and... Read MoreMar 17, 2022
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Wikswo, VIIBRE team on track to build third-generation ‘self-driving lab’ with $1M from NSF
John Wikswo, founder and director of the Vanderbilt Institute for Integrative Biosystems Research and Education and Gordon A. Cain University Professor, is the principal investigator of a $1 million award from the National Science Foundation. The object is to build a pathbreaking “robot scientist”—a fully automated microfluidic system for parallel, independent, long-duration, machine-guided experiments. The... Read MoreMar 5, 2022
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Wikswo, VIIBRE team on track to build third-generation ‘self-driving lab’ with $1M from NSF
John Wikswo, founder and director of the Vanderbilt Institute for Integrative Biosystems Research and Education and Gordon A. Cain University Professor, is the principal investigator of a $1 million award from the National Science Foundation. The object is to build a pathbreaking “robot scientist”—a fully automated microfluidic system for parallel, independent, long-duration, machine-guided experiments. The... Read MoreMar 5, 2022
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International research collaboration reveals new possibilities in nanophotonics
Joshua Caldwell, Flowers Family Chancellor’s Faculty Fellow in Engineering and associate professor of mechanical engineering, and Joseph Matson, a graduate student in Caldwell’s lab, have contributed to an international study that has discovered a new type of light-matter coupling. The work has long-term implications for how optical components can be even further miniaturized, a discovery... Read MoreMar 3, 2022
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Probing cancer cell invasion
The rigidity of the extracellular matrix that surrounds cells impacts the contractile and invasive properties of head and neck cancer cells. Read MoreMar 1, 2022
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Invasive strep can defy zinc toxicity
Vanderbilt researchers find that invasive Group B Streptococcus strains, a significant risk to pregnant patients and infants, can grow in presence of toxic zinc levels. Read MoreFeb 28, 2022
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Researchers test and validate platform for potential PPE tracking across U.S. hospitals
A multidisciplinary team that includes a Vanderbilt computer science professor has established the foundation for an automated, up-to-date assessment of personal protective equipment across U.S. hospitals—work that got its start before the COVID-19 pandemic but took on greater urgency. Significantly, the team developed a secure, third-party system to operate independent of federal and state governments... Read MoreFeb 25, 2022
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PET imaging probe for Alzheimer’s disease
Vanderbilt researchers report on a new PET imaging probe that will be useful for exploring Alzheimer’s disease pathology. Read MoreFeb 24, 2022
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Multicenter team seeks to create at-home artificial lung system
Vanderbilt team to focus on engineering, testing the device by Matt Batcheldor Vanderbilt University Medical Center will share in an $8.7 million federal grant to create an artificial lung system that patients with incurable lung disease can use at home. The Department of Defense Congressionally Directed Medical Research Program (CDMRP) grant will fund research to create... Read MoreFeb 24, 2022
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Predicting brain cancer outcome
Red blood cell distribution width has prognostic value for many diseases, but it was not associated with overall survival in patients with glioblastoma, Vanderbilt researchers found. Read MoreFeb 15, 2022
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Diverticulitis surgery: guidelines needed
Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read MoreFeb 10, 2022
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Gene variants increase risk of kidney failure in Black veterans with COVID-19: study
Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read MoreFeb 10, 2022
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VUMC study raises hope for improving treatment of kidney disease
Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read MoreFeb 2, 2022
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Accelerating podocyte production
A new method developed by Vanderbilt researchers to generate kidney cells from stem cells offers a faster and less expensive way to make these valuable tools for studying kidney diseases. Read MoreFeb 1, 2022
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Impact of digital health interventions
Vanderbilt researchers test and recommend statistical approaches to study the association between engagement with digital health interventions and clinical outcomes. Read MoreJan 31, 2022
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White matter and psychosis
The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read MoreJan 27, 2022
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Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read MoreJan 27, 2022
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Breakthrough measurements/theory of vibrating atoms in nanostructures ushers in new class of technology
Vanderbilt researchers Sokrates Pantelides and Joshua Caldwell are part of an international collaboration that has demonstrated a new way to manipulate and measure subtle atomic vibrations in nanomaterials. This breakthrough could make it possible to develop customized functionalities to improve on and build new technologies. Sokrates Pantelides (Vanderbilt University) Joshua Caldwell (Vanderbilt University) Electron beams... Read MoreJan 26, 2022
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New method enhances efforts to identify drug repurposing targets
Researchers at Vanderbilt University Medical Center have developed a new method for identifying drugs for the repurposing trials that can lead to new indications for drugs already in use. Read MoreJan 20, 2022