NIH
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Diet and colorectal cancer risk
Higher dietary intake of antioxidant compounds found in fruits, vegetables, teas and spices was associated with lower risk of colorectal cancer, and intake was lower among Black participants, potentially contributing to colorectal cancer health disparities. Read MoreFeb 14, 2022
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Diverticulitis surgery: guidelines needed
Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read MoreFeb 10, 2022
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Impact of digital health interventions
Vanderbilt researchers test and recommend statistical approaches to study the association between engagement with digital health interventions and clinical outcomes. Read MoreJan 31, 2022
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White matter and psychosis
The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read MoreJan 27, 2022
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Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read MoreJan 27, 2022
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Study identifies molecular trigger of severe injury-induced inflammatory response
Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure. Read MoreJan 19, 2022
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Ensuring the “best possible” medication history
About 80% of hospital admission electronic records were missing a drug prescribed to an older adult, Vanderbilt researchers found, highlighting the need for a multipronged approach to address medication discrepancies and support safe prescribing practices. Read MoreJan 18, 2022
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H. pylori, lipid loss and stomach cancer
H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read MoreJan 17, 2022
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The role of integrins in kidney “integrity”
Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered. Read MoreJan 13, 2022
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Salmonella overcomes host resistance
The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization. Read MoreJan 13, 2022
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Vanderbilt joins TSU, Meharry and the Congregational Health and Education Network on $4M NIH grant to address social factors in health
Sharon Jones, assistant professor of nursing, and David G. Schlundt, associate professor of psychology, are participating in a collaborative research project to address health disparities and advance health equity in Nashville. Read MoreJan 11, 2022
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Oral microbes and gastric cancer
Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development. Read MoreDec 13, 2021
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Cell signaling targets in leukemia
Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read MoreDec 9, 2021
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Prostate cancer treatment regret
Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity. Read MoreDec 9, 2021
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CRISPR screen identifies new anti-inflammatory drug target
A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics. Read MoreNov 11, 2021
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The power of white matter
Using a novel analysis of fMRI data, Vanderbilt researchers discovered intriguing patterns of signals in the brain’s white matter, the “conduit” for relaying signals between different brain regions. Read MoreNov 11, 2021
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$8 million NIH grant awarded to Vanderbilt researchers for study of infant/child brain development
Vanderbilt faculty members Laurie Cutting and Sarah Osmundson will lead an $8 million grant from the National Institutes of Health as part of a groundbreaking, multi-institutional overview of variables influencing infant and child brain development, including substance exposure. Read MoreNov 2, 2021
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Chang receives $1.1M grant to investigate brain-body connections, advance understanding of how brains age
Catie Chang, assistant professor of electrical and computer engineering, has received a $1.1 million NIH grant to investigate brain-body connections and advance understanding of aging in normal and pathological brains. Read MoreOct 18, 2021
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Landman awarded $2.6M grant to improve Alzheimer’s patient management
Professor of Electrical and Computer Engineering Bennett Landman has received a $2.6 million NIH grant to improve the understanding of structural changes in the brains of people who have Alzheimer’s disease. Read MoreOct 15, 2021
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Chang receives $1.1 million grant to investigate brain-body connections, advance understanding of how brains age
An assistant professor of electrical and computer engineering has received a $1.1 million NIH grant to investigate brain-body connections and advance understanding of aging in normal and pathological brains. Catie Chang, assistant professor of electrical and computer engineering, leads the research team, which will focus on developing machine learning methods that can automatically reconstruct physiological... Read MoreOct 11, 2021