NIH

Surgical removal of the colon for recurrent diverticulosis varies by geographic region and is associated with surgeon and hospital factors; stronger national guidelines are needed, Vanderbilt researchers report. Read More

Vanderbilt researchers test and recommend statistical approaches to study the association between engagement with digital health interventions and clinical outcomes. Read More

The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read More

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read More

Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure. Read More

About 80% of hospital admission electronic records were missing a drug prescribed to an older adult, Vanderbilt researchers found, highlighting the need for a multipronged approach to address medication discrepancies and support safe prescribing practices. Read More

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read More

Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered. Read More

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization. Read More

Studies in three large population cohorts that include Asian, African American and European American people support a role for the oral microbiota — the collection of microbial species in the mouth — in gastric cancer development. Read More

Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read More

Vanderbilt researchers suggest that to reduce treatment-related regret for men with localized prostate cancer, treatment preparation should focus on shared decision-making and aligning patient expectations with treatment toxicity. Read More

An assistant professor of electrical and computer engineering has received a $1.1 million NIH grant to investigate brain-body connections and advance understanding of aging in normal and pathological brains. Catie Chang, assistant professor of electrical and computer engineering, leads the research team, which will focus on developing machine learning methods that can automatically reconstruct physiological... Read More

Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered. Read More

Vanderbilt psychiatrists are probing brain circuit hyperactivity implicated in schizophrenia, with the idea that normalizing the hyperactivity may improve cognitive processes. Read More

Vanderbilt epidemiologists conducted in-depth whole genome sequencing of breast cancer risk genes in Black women, who die at higher rates and have more aggressive disease, to discover mutations that may improve testing and treatment selection. Read More

A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered. Read More

New acquisition and reconstruction solutions for ultrasound imaging developed by a Vanderbilt team aim to fundamentally improve the ability to obtain high quality, clinically relevant images, especially in cases of heart disease. With a new, $2.3 million National Institutes of Health grant, the researchers will evaluate their advances on a specific subset of cardiac imaging... Read More

A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to... Read More

A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to... Read More